Evidence map›Paper›PMID 36228984›Full record

ArticleContemporary clinical trials2022

Stepped care for suicide prevention in teens and young adults: Design and methods of a randomized controlled trial.

Christina R Sheppler, Anna C Edelmann, Alison J Firemark, Catherine A Sugar, Frances L Lynch, John F Dickerson, Jeanne M Miranda, Gregory N Clarke, Joan R Asarnow

2 registry-linked trialsOpen access · greenAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01379027 nacompletednot on this map

Internet CBT for Depression: Comparing Pure, Guided, and Stepped Care

TypeinterventionalSponsorKaiser PermanenteRan2011 to 2016Enrolled1,816ConditionsDepressionArmsPure self-help Internet CBT for depression, Guided self-help Internet CBT, Stepped-Care Internet CBT condition
NCT03092271 nacompletednot on this map

Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young Adults

TypeinterventionalSponsorUniversity of California, Los AngelesRan2017 to 2022Enrolled301ConditionsSuicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, SuicideArmsStepped Care for Suicide Prevention, Zero Suicide Quality Improvement
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Christina R ShepplerKaiser Permanente Northwest, Center for Health Research, United States of America. Electronic address: Christina.R.Sheppler@kpchr.org.
Anna C EdelmannKaiser Permanente Northwest, Center for Health Research, United States of America. Electronic address: Anna.C.Edelmann@kpchr.org.
Alison J FiremarkKaiser Permanente Northwest, Center for Health Research, United States of America. Electronic address: Alison.J.Firemark@kpchr.org.
Catherine A SugarUniversity of California, Los Angeles, Departments of Biostatistics, Statistics, and Psychiatry, United States of America. Electronic address: csugar@ucla.edu.
Frances L LynchKaiser Permanente Northwest, Center for Health Research, United States of America. Electronic address: Frances.Lynch@kpchr.org.
John F DickersonKaiser Permanente Northwest, Center for Health Research, United States of America. Electronic address: John.F.Dickerson@kpchr.org.
Jeanne M MirandaUniversity of California, Los Angeles, Department of Psychiatry and Biobehavioral Sciences, United States of America. Electronic address: jmmiranda@mednet.ucla.edu.
Gregory N ClarkeKaiser Permanente Northwest, Center for Health Research, United States of America. Electronic address: Greg.Clarke@kpchr.org.
Joan R AsarnowUniversity of California, Los Angeles, Department of Psychiatry and Biobehavioral Sciences, United States of America. Electronic address: JAsarnow@mednet.ucla.edu.
Kaiser Permanente · USUniversity of California, Los Angeles · US

Funding

Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young AdultsR01MH112147 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ASARNOW, JOAN ROSENBAUM, CLARKE, GREGORY N · 2016 to 2022
$5.3M
NIMH NIH HHS R01 MH112147
6 · The paper itself

Abstract

backgroundSuicide is the second‑leading cause of death among adolescents and young adults in the United States, with rates rising over much of the last decade. The design, testing, and implementation of interventions to prevent suicide in this population is a public health priority. This manuscript outlines the design and methods for a research study that compares two interventions aimed at reducing suicide and suicide attempts in youth.

methodsWe will enroll 300 youth aged 12-24 at high risk for suicide in this randomized controlled parallel group superiority trial. Participants will be randomly assigned to one of two study arms: (1) Zero Suicide Quality Improvement (ZSQI) implemented within the Kaiser Permanente Northwest (KPNW) health system, or (2) ZSQI plus a stepped care intervention for suicide prevention (SC-SP), where the services offered (including care management and dialectical behavior therapy [DBT]) increase based on risk level. Outcomes will be assessed at baseline, as well as 3-, 6-, and 12-months post randomization. The study was conceptualized and designed collaboratively by investigators at UCLA and KPNW.

resultsTo be reported in future manuscripts.

conclusionThe main objective of the study is to determine whether the SC-SP intervention is superior to ZSQI with regard to lowering rates of fatal and nonfatal suicide attempts. Interventions that incorporate the latest research need to be designed and tested under controlled conditions to make progress toward the goal of achieving zero suicide. The results from this trial will directly inform those efforts.

trial registrationCLINICALTRIALS: gov, NCT03092271, https://clinicaltrials.gov/ct2/show/NCT03092271https://clinicaltrials.gov/ct2/show/NCT01379027.

Indexed as

Suicide, AttemptedAdolescentEquivalence Trials as TopicHumansRandomized Controlled Trials as TopicTreatment OutcomeYoung AdultAdolescentsDialectical behavior therapyRandomized controlled trialSelf-injurious behaviorSuicideYoung adults

Identifiers

PMID36228984
PMCPMC10832890
OpenAlexW4304128193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.