ArticleThe American journal of tropical medicine and hygiene2022
Scientific Findings of the Southern and Central Africa International Center of Excellence for Malaria Research: Ten Years of Malaria Control Impact Assessments in Hypo-, Meso-, and Holoendemic Transmission Zones in Zambia and Zimbabwe.
Article in The American journal of tropical medicine and hygiene, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The trial behind it
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Prevalence and factors associated with malaria amongst under-five children in Senga Hill District, Northern Province, Zambia, a community-based cross-sectional study.Malaria journal · 2026Article
- Species composition and blood feeding patterns of understudied Anopheles mosquitoes in southern Zambia, an area of low malaria transmission.Malaria journal · 2026Article
- False-positive and false-negative malaria rapid diagnostic test results: evidence from a nationally representative survey of children in Ghana.Malaria journal · 2026Article
- Malaria outbreak prediction at the sub-district level in Zambia using remote sensing satellite data.Malaria journal · 2025Article
- Program Evaluation of Community Case Management with Reactive Test and Treat for Malaria in a High-Transmission Setting.The American journal of tropical medicine and hygiene · 2025Article
- CCM and RTAT Malaria Interventions.The American journal of tropical medicine and hygiene · 2025Article
- Impact of Climate Change on Malaria Transmission and Management in Zimbabwe: A Scoping Review of the Literature.Health services insights · 2025Review
- Risk factors for contracting malaria in six wards of Mudzi District, Zimbabwe: A case control-study.PloS one · 2025Article
- Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates in Plasmodium falciparum.EBioMedicine · 2024Article
- Association between indoor residual spraying and the malaria burden in Zambia and factors associated with IRS refusals: a case-control study in Vubwi District.Parasites & vectors · 2024Article
- Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates inmedRxiv : the preprint server for health sciences · 2024Article
- Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia.Communications medicine · 2024Article
- Genomics reveals heterogeneousmedRxiv : the preprint server for health sciences · 2024Article
- Community perceptions, acceptability, and the durability of house screening interventions against exposure to malaria vectors in Nyimba district, Zambia.BMC public health · 2024Article
- Molecular detection and phylogenetic characterization ofScience in One Health · 2024Article
- Cost and cost effectiveness of geospatial planning and delivery tools added to standard health campaigns in Luapula Province, Zambia.Oxford open digital health · 2024Article
- Supplementing routine hospital surveillance of malaria to capture excess mortality and epidemiological trends: a five-year observational study.Frontiers in malaria · 2024Article
- Advances in the genetic characterization of the malaria vector, Anopheles funestus, and implications for improved surveillance and control.Malaria journal · 2023Review
- Declining Age-Specific Seroprevalence and Seroconversion Rates in Plasmodium falciparum from 2009 to 2018 Documents Progress toward Malaria Elimination in Southern Zambia.The American journal of tropical medicine and hygiene · 2023Article
- Anopheles rufipes implicated in malaria transmission both indoors and outdoors alongside Anopheles funestus and Anopheles arabiensis in rural south-east Zambia.Malaria journal · 2023Article
Corrections and comments
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Authors and funding
37 authors at 10 institutions in 4 countries.
Funding
Abstract
For a decade, the Southern and Central Africa International Center of Excellence for Malaria Research has operated with local partners across study sites in Zambia and Zimbabwe that range from hypo- to holoendemic and vary ecologically and entomologically. The burden of malaria and the impact of control measures were assessed in longitudinal cohorts, cross-sectional surveys, passive and reactive case detection, and other observational designs that incorporated multidisciplinary scientific approaches: classical epidemiology, geospatial science, serosurveillance, parasite and mosquito genetics, and vector bionomics. Findings to date have helped elaborate the patterns and possible causes of sustained low-to-moderate transmission in southern Zambia and eastern Zimbabwe and recalcitrant high transmission and fatality in northern Zambia. Cryptic and novel mosquito vectors, asymptomatic parasite reservoirs in older children, residual parasitemia and gametocytemia after treatment, indoor residual spraying timed dyssynchronously to vector abundance, and stockouts of essential malaria commodities, all in the context of intractable rural poverty, appear to explain the persistent malaria burden despite current interventions. Ongoing studies of high-resolution transmission chains, parasite population structures, long-term malaria periodicity, and molecular entomology are further helping to lay new avenues for malaria control in southern and central Africa and similar settings.
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Registered trials
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