Evidence map›Paper›PMID 36228696›Full record

ArticleGastrointestinal endoscopy2023

Expanding the role of pneumatic dilation for nonachalasia patients: a comparative study.

Nikita Desai, Meredith Kline, Debra Duncan, Marie Godiers, Vaishali Patel, Steven Keilin, Anand S Jain

Open access · greenAbstract read
In one paragraph

Article in Gastrointestinal endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nikita DesaiDepartment of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
Meredith KlineEmory University School of Medicine, Atlanta, Georgia, USA.
Debra DuncanEmory University School of Medicine, Atlanta, Georgia, USA.
Marie GodiersDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Vaishali PatelDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Steven KeilinDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Anand S JainDepartment of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.
Emory University · US

Funding

Fibrosis of the Lower Esophageal Sphincter in AchalasiaK23DK131317 · NIDDK · EMORY UNIVERSITY · PI Anand Sagar Jain · 2022 to 2026
$772k
NIDDK NIH HHS K23 DK131317
6 · The paper itself

Abstract

BACKGROUND AND

aimsTreatment options for nonachalasia obstructive disorders of the esophagogastric junction (EGJ) are limited. The aim of this study was to assess the treatment efficacy of pneumatic dilation (PD) for the disorders of EGJ outflow obstruction (EGJOO) and postfundoplication EGJ obstruction (PF-EGJO) and to assess attitudes regarding training in PD.

methodsThis was a 2-part study. The main study was a prospective, single-center study comparing treatment outcomes after PD in patients with EGJOO and PF-EGJO, defined using manometry criteria, versus achalasia. Treatment success was defined as a post-PD Eckardt score (ES) of ≤2 at the longest duration of follow-up available. In a substudy, a 2-question survey was sent to 78 advanced endoscopy fellowship sites in the United States regarding training in PD.

resultsOf the 58% of respondents to the advanced endoscopy program director survey, two-thirds reported no training in PD at their program. The primary rationale cited was lack of a clinical need for PD. Sixty-one patients (15 achalasia, 32 EGJOO, and 14 PF-EGJO) were included in the main study with outcomes available at a mean follow-up of 8.8 months. Overall, mean ES decreased from 6.30 to 2.89 (P < .0001), and a mean percentage of improvement in symptoms reported by patients was 55.3%. ES ≤2 was achieved by 33 of 61 patients (54.1%).

conclusionsPD is an effective treatment for the nonachalasia obstructive disorders of the EGJ. There may be a current gap in training and technical expertise in PD.

Indexed as

Esophageal AchalasiaEsophageal Motility DisordersDilatationEsophagogastric JunctionHumansManometryProspective Studies

Identifiers

PMID36228696
PMCPMC11273289
OpenAlexW4304123978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.