SynthesisDigestive diseases (Basel, Switzerland)2023
Computed Tomography-Defined Fat Composition as a Prognostic Marker in Gastric Adenocarcinoma: A Systematic Review and Meta-Analysis.
Synthesis in Digestive diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Visceral fat area as a prognostic biomarker in gastric cancer: a systematic review and meta-analysis of survival outcomes.Frontiers in oncology · 2025Pooled it
- Effect of Preoperative Sarcopenic Obesity on Outcomes in Patients with Gastric Cancer After Surgery.Cancers · 2026Article
- Visceral adiposity rather than BMI predicts overall survival after curative gastrectomy for gastric cancer: a retrospective cohort study with age-stratified analyses.Frontiers in medicine · 2026Article
- Study on the prediction of postoperative metastasis in renal cancer using perirenal fat CT radiomics combined with clinical features.Frontiers in oncology · 2026Article
- Subcutaneous adipose tissue [European journal of nuclear medicine and molecular imaging · 2025Article
- [Prognostic value of body composition in oncological visceral surgery].Chirurgie (Heidelberg, Germany) · 2025Review
- Body mass index and survival among patients with advanced biliary tract cancer: a single-institutional study with nationwide data-based validation.Journal of gastroenterology · 2024Article
- Triglyceride-glucose index as a marker for visceral obesity in patients with gastric cancer.Frontiers in nutrition · 2024Article
- Computed Tomography-based Assessment of Visceral Fat for Predicting Intra-abdominal Infectious Complications After Gastrectomy in Patients With Gastric Cancer.In vivo (Athens, Greece)Article
Corrections and comments
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4 authors.
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Abstract
backgroundComputed tomography (CT)-defined fat quantification has been an emergent field of research in oncology. It was shown that this parameter is predictive and prognostic of several clinically relevant factors in several tumor entities.
objectiveOur aim was to establish the effect of visceral (VFA) and subcutaneous fat areas (SFA) on overall survival (OS), disease-free survival (DFS), and postoperative complications in gastric cancer patients based on a large patient sample.
methodsMEDLINE library, EMBASE, and SCOPUS databases were screened for the associations between VFA and SFA defined by CT images and OS, DFS, and postoperative complications in gastric cancer patients up to August 2022. The primary endpoint of the systematic review was the hazard ratio for the outcome parameters. High VFA was, in most studies, defined by the threshold value of 100 cm2. In total, 9 studies were suitable for the analysis and included in the present study.
resultsThe included studies comprised 3,713 patients. The identified frequency of visceral obesity was 44.9%. The pooled hazard ratio for the effect of high VFA on OS was 1.28 (95% CI 1.09-1.49, p = 0.002). For SFA, it was 1.87 (95% CI 1.45-2.42, p < 0.0001). The pooled hazard ratio for the influence of high VFA on DFS was 1.17 (95% CI 0.95-1.43, p = 0.14). The pooled odds ratio for the associations between VFA and postoperative complications was 1.36 (95% CI 1.09-1.69, p = 0.006).
conclusionCT-defined VFA and SFA influence OS in patients with gastric cancer. VFA also influences the occurrence of postoperative complications. Therefore, assessment of fat areas should be included in clinical routine in patients with gastric cancer.
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