Evidence map›Paper›PMID 36228339›Full record

ReviewThe Journal of surgical research2023

A Review of Immune Checkpoint Blockade for the General Surgeon.

Xavier L Baldwin, Philip M Spanheimer, Stephanie Downs-Canner

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of surgical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Xavier L BaldwinDepartment of Surgery, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Philip M SpanheimerDepartment of Surgery, University of North Carolina School of Medicine, Chapel Hill, North Carolina.
Stephanie Downs-CannerDepartment of Surgery, Breast Service, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: downscas@mskcc.org.
University of North Carolina at Chapel Hill · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Duke-UNC Chapel Hill Immunotherapy Training GrantT32CA211056 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHAO, NELSON J., SERODY, JONATHAN S. · 2017 to 2021
$2.2M
The role of B-cells in the anti-tumor immune response in triple negative breast cancerK08CA259533 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Stephanie M Downs-Canner · 2022 to 2026
$1.2M
NCI NIH HHS K08 CA259533NCI NIH HHS P30 CA008748NCI NIH HHS T32 CA211056
6 · The paper itself

Abstract

The immune system is a complex and interconnected system that has evolved to protect its host from foreign pathogens. CD8

Indexed as

NeoplasmsSurgeonsCD8-Positive T-LymphocytesHumansImmune Checkpoint InhibitorsImmunotherapyImmune Checkpoint InhibitorsCheckpoint inhibitionCytotoxic T cellImmunotherapyT cell

Identifiers

PMID36228339
PMCPMC10029124
OpenAlexW4304087151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.