Observational studyJournal of substance abuse treatment2022
Longitudinal associations between pain and substance use disorder treatment outcomes.
Observational study in Journal of substance abuse treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Exploring chronic pain and other clinical characteristics in drug treatment court participants.Substance abuse treatment, prevention, and policy · 2026Article
- Pain assessment tools in patients with substance use disorders: a systematic scoping review.Addiction science & clinical practice · 2026Article
- A qualitative study on cannabis use for harm reduction and pain among veterans enrolled in an SUD treatment program.Harm reduction journal · 2026Article
- Pain and Cognitive Concerns Among Breast Cancer Survivors: The Mediating Role of Substance Use Coping.Cancer medicine · 2025Article
- Association between chronic pain and substance use.Scientific reports · 2025Article
- Clinical and psychosocial changes in adults with opioid use disorder and chronic pain using medical cannabis: a brief report.Journal of cannabis research · 2025Article
- Exploring Passion for Opioid Use with a Treatment-Seeking Sample: Results from a Canonical Correlation Analysis.Addiction research & theory · 2025Article
- Recent advances in the treatment of chronic pain and substance use disorders.Current opinion in psychology · 2025Review
- The Role of Endogenous Beta-Endorphin and Enkephalins in the Crosstalk Between Ethanol and Morphine.Pharmaceuticals (Basel, Switzerland) · 2025Article
- The Dynorphin/-Opioid Receptor System at the Interface of Hyperalgesia/Hyperkatifeia and Addiction.Current addiction reports · 2025Review
- Associations of discomfort intolerance, discomfort avoidance, and cannabis and alcohol use among persons with chronic pain receiving prescription buprenorphine for opioid use disorder.Drug and alcohol dependence · 2024Article
- Pain Predicts Dropout From Substance Use Treatment.Journal of studies on alcohol and drugs · 2024Article
- Neural and Psychosocial Mechanisms Underlying Alcohol Use and Pain Interactions: Overview of Current Evidence and Future Directions.Current addiction reports · 2023Article
- Latent patterns of sleep disturbance, pain impact, and depressive symptoms in residential substance use treatment.Drug and alcohol dependence · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
introductionPain is commonly reported among those in treatment for substance use disorders (SUD) and is associated with poorer SUD treatment outcomes. The current study examined the trajectory of pain over the course of SUD treatment and associations with substance use outcomes.
methodsThis observational study included adults seeking treatment for alcohol, cannabis, or opioid use disorders (N = 811). Participants completed a battery of assessments at treatment admission, 30 days post admission, and at discharge, including measures of demographics, pain, quality of life, abstinence self-efficacy, and craving.
resultsAnalyses indicated linear reductions in pain intensity and interference over time. Significant interactive effects were observed for opioid use disorder (OUD) and time, such that participants with OUD had greater reductions in pain intensity and interference over time compared to those without OUD. Elevated pain intensity was associated with negative treatment outcomes, including reduced quality of life and abstinence self-efficacy, and greater craving and negative affect.
conclusionsReductions in pain occur over the course of SUD treatment, particularly for those with OUD. Greater pain was also associated with adverse SUD treatment outcomes. Results suggest that treatment and associated abstinence may be beneficial for those with co-occurring pain and SUD, highlighting an additional benefit of improving access to SUD treatment for patients and health care systems. Future research should replicate these findings among diverse samples and further characterize the trajectory of pain during and after SUD treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.