Evidence map›Paper›PMID 36228007›Full record

ArticlePloS one2022

Social connectedness as a determinant of mental health: A scoping review.

Priya J Wickramaratne, Tenzin Yangchen, Lauren Lepow, Braja G Patra, Benjamin Glicksburg, Ardesheer Talati, Prakash Adekkanattu, Euijung Ryu, Joanna M Biernacka, Alexander Charney and 4 more

Erratum issuedAbstract readScoping Review
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 165 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. The Experiences of Social Connection and Isolation in Adults With Acquired Brain Injury: A Qualitative Systematic Review and Metasynthesis.Health expectations : an international journal of public participation in health care and health policy · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Catalyst for change: Psilocybin's antidepressant mechanisms-A systematic review.Journal of psychopharmacology (Oxford, England) · 2025
    Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Article
  20. Article

105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Priya J WickramaratneDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID 0000-0002-6214-5147
Tenzin YangchenDivision of Translational Epidemiology, New York State Psychiatric Institute, New York, NY, United States of America.
Lauren LepowDepartments of Psychiatry and Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Braja G PatraDivision of Health Informatics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States of America.ORCID 0000-0003-2997-5314
Benjamin GlicksburgDepartments of Psychiatry and Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Ardesheer TalatiDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States of America.
Prakash AdekkanattuDepartment of Information Technologies and Services, Weill Cornell Medicine, New York, NY, United States of America.
Euijung RyuDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, United States of America.
Joanna M BiernackaDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, United States of America.
Alexander CharneyDepartments of Psychiatry and Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
J John MannDivision of Molecular Imaging and the Neuropathology, Departments of Psychiatry and Radiology, New York State Psychiatric Institute, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States of America.
Jyotishman PathakDivision of Health Informatics, Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States of America.
Mark OlfsonDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States of America.
Myrna M WeissmanDepartment of Psychiatry, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States of America.ORCID 0000-0003-3490-3075

Funding

4/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disordersR01MH121922 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PATHAK, JYOTISHMAN · 2019 to 2023
$2.0M
2/4: Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disordersR01MH121924 · NIMH · MAYO CLINIC ROCHESTER · PI BIERNACKA, JOANNA M · 2019 to 2024
$2.0M
Multi-modal unsupervised embeddings to advance machine learning in healthcareR01LM013766 · NLM · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CAMPANELLA, GABRIELE · 2022 to 2025
$1.4M
1/4 Leveraging EHR-linked biobanks for deep phenotyping, polygenic risk score modeling, and outcomes analysis in psychiatric disordersR01MH121921 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANN, JOSEPH JOHN, OLFSON, MARK · 2019 to 2023
$1.3M
NIMH NIH HHS R01 MH121921NIMH NIH HHS R01 MH121922NIMH NIH HHS R01 MH121924NLM NIH HHS R01 LM013766
6 · The paper itself

Abstract

Public health and epidemiologic research have established that social connectedness promotes overall health. Yet there have been no recent reviews of findings from research examining social connectedness as a determinant of mental health. The goal of this review was to evaluate recent longitudinal research probing the effects of social connectedness on depression and anxiety symptoms and diagnoses in the general population. A scoping review was performed of PubMed and PsychInfo databases from January 2015 to December 2021 following PRISMA-ScR guidelines using a defined search strategy. The search yielded 66 unique studies. In research with other than pregnant women, 83% (19 of 23) studies reported that social support benefited symptoms of depression with the remaining 17% (5 of 23) reporting minimal or no evidence that lower levels of social support predict depression at follow-up. In research with pregnant women, 83% (24 of 29 studies) found that low social support increased postpartum depressive symptoms. Among 8 of 9 studies that focused on loneliness, feeling lonely at baseline was related to adverse outcomes at follow-up including higher risks of major depressive disorder, depressive symptom severity, generalized anxiety disorder, and lower levels of physical activity. In 5 of 8 reports, smaller social network size predicted depressive symptoms or disorder at follow-up. In summary, most recent relevant longitudinal studies have demonstrated that social connectedness protects adults in the general population from depressive symptoms and disorders. The results, which were largely consistent across settings, exposure measures, and populations, support efforts to improve clinical detection of high-risk patients, including adults with low social support and elevated loneliness.

Indexed as

Major Depressive DisorderAdultAnxiety DisordersDepressionFemaleHumansLonelinessMental HealthPregnancySocial Support

Identifiers

PMID36228007
PMCPMC9560615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.