Trial reportPloS one2022
The analgesic efficacy of pericapsular nerve group block in patients with intertrochanteric femur fracture: A randomized controlled trial.
Trial report in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06443892 (Comparison of Postoperative Analgesic Efficacy of Pericapsular Nerve Block), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Postoperative Analgesic Efficacy of Pericapsular Nerve Block (PENG) and Suprainguinal Fascia Iliaca Compartment Block(SFICB) in Intertrochanteric Femur Fractures
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Fascia iliaca compartment block for postoperative hip fracture pain: a systematic review and meta-analysis of randomized controlled trials.BMC anesthesiology · 2026Pooled it
- The postoperative analgesic efficacy of three peripheral nerve blocks in hip fracture surgery: a systematic review and meta-analysis of randomised trials.Archives of orthopaedic and trauma surgery · 2026Pooled it
- Functional recovery and pain control following Pericapsular Nerve Group (PENG) block following hip surgeries: a systematic review and meta-analysis of randomised controlled trials.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Comparing the pericapsular nerve group block and fascia iliaca block for acute pain management in patients with hip fracture: a randomised clinical trial.Anaesthesia · 2025Trial
- Effectiveness of pericapsular nerve group block for hip fracture pain management in the emergency department: results of the ED-PENG-B randomised controlled trial.BMC emergency medicine · 2025Trial
- Comparison of Ultrasound-Guided Pericapsular Nerve Group Block Versus Intravenous Ketamine for Positional Pain Management Before Spinal Anesthesia in Patients Who Underwent Hip Fracture Surgery: A Randomized Controlled Trial.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- [Perioperative management of trochanteric femoral fractures : Fasting, fluid therapy and multimodal pain management as underappreciated factors].Unfallchirurgie (Heidelberg, Germany) · 2026Review
- Postoperative analgesic outcomes of fascia iliaca compartment block versus pericapsular nerve group block in hip fracture surgery: a retrospective observational study.BMC anesthesiology · 2026Observational
- Reappraising the fascia iliaca compartment block and pericapsular nerve group block for geriatric hip fractures: a narrative review.Journal of anesthesia, analgesia and critical care · 2026Review
- Acute pain management in older adults presenting to the emergency department: a clinical review.Singapore medical journal · 2026Review
- A Bayesian network meta-analysis of peripheral nerve blocks for postoperative analgesia in adults following hip fracture surgery.BMC surgery · 2026Article
- Article
- Regional Anesthesia Strategies in Orthopedic Trauma.Orthopedic reviews · 2026Article
- Article
- Comparison between femoral nerve block and pericapsular nerve group block as preemptive analgesia in geriatric intertrochanteric fractures: A prospective randomised controlled clinical trial.Journal of orthopaedics · 2025Article
- Regional Nerve Block for Hip Fracture Surgery in an Elderly Patient With Severe Aortic Stenosis: A Case Report.Cureus · 2025Article
- Efficacy and Safety of Pericapsular Nerve Group Block (PENG) in Hip Surgery Under General Anaesthesia: A Systematic Literature Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Pericapsular Nerve Group Block for Hip Fracture Pain Management: A Narrative Review of Emergency Applications.Journal of pain research · 2025Review
- Article
- Is pericapsular nerve group block superior to other regional analgesia techniques following total hip arthroplasty? a systematic review and network meta-analysis.Perioperative medicine (London, England) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study is to evaluate analgesic efficacy of pericapsular nerve group (PENG) block in patients with intertrochanteric femur fracture (IFF).
methodsThis double-blinded randomized controlled trial in patients with IFF scheduled for proximal femoral nail antirotation (PFNA) between December 2020 and November 2021. The primary outcome was VAS scores during exercising at 6 h after surgery; secondary outcomes were pain during exercising and rest, intraoperative dose of remifentanil, cumulative dose of postoperative fentanyl, postoperative analgesia satisfaction scores, and ratio of quadriceps weakness.
resultsA total of 50 patients were randomly divided into PENG block group (n = 25) or fascia iliaca compartment block (FICB) group (n = 25). Exercising VAS scores at 6 h after surgery were significantly lower in PENG block group than that in FICB group (2 (2, 4) vs. 6 (4, 7), P < 0.001). The intraoperative dose of remifentanil and cumulative dose of postoperative fentanyl by patient-controlled intravenous analgesia within 24 h after surgery in PENG block group were significantly lower than in FICB group (both P < 0.001). Postoperative analgesia satisfaction scores in PENG block group were significantly higher than those in FICB group (P = 0.016). The ratio of quadriceps weakness at 6 h after surgery was significantly higher in FICB group than PENG block group (48% vs. 0%, P < 0.001).
conclusionsCompared to FICB, ultrasound-guided PENG block may provide better postoperative pain relief in patients with IFF, with less pronounced quadriceps weakness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.