Evidence map›Paper›PMID 36227523›Full record

ArticleInflammation2023

The Influenza-Induced Pulmonary Inflammatory Exudate in Susceptible Tpl2-Deficient Mice Is Dictated by Type I IFN Signaling.

Krishna Latha, Yesha Patel, Sanjana Rao, Wendy T Watford

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. TPL2 kinase activity is required forFrontiers in immunology · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Krishna LathaDepartment of Infectious Diseases, University of Georgia, Athens, GA, USA.
Yesha PatelDepartment of Cell Biology, University of Georgia, Athens, GA, USA.
Sanjana RaoDepartment of Genetics, University of Georgia, Athens, GA, USA.
Wendy T WatfordDepartment of Infectious Diseases, University of Georgia, Athens, GA, USA. watfordw@uga.edu.
University of Georgia · US

Funding

Regulation of mucosal immunity to respiratory viruses by Tpl2R21AI147003 · NIAID · UNIVERSITY OF GEORGIA · PI WATFORD, WENDY T · 2019 to 2020
$415k
NIAID NIH HHS R21 AI147003NIH HHS R21AI147003
6 · The paper itself

Abstract

The most prominent host response to viral infection is the production of type 1 interferons (T1 IFNs). One host regulator of the T1 IFNs is the serine-threonine kinase, tumor progression locus 2 (TPL2). We have previously demonstrated that Tpl2

Indexed as

Influenza, HumanAnimalsCytokinesExudates and TransudatesHumansLungMAP Kinase Kinase KinasesMiceMice, Inbred C57BLMice, KnockoutNeutrophilsCytokinesMAP Kinase Kinase KinasesInfluenzaInterferonsNeutrophilsTPL2

Identifiers

PMID36227523
PMCPMC9558022
OpenAlexW4304890916

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.