Evidence map›Paper›PMID 36227454›Full record

ArticleEndocrine pathology2022

The Significance of RAS-Like Mutations and MicroRNA Profiling in Predicting Malignancy in Thyroid Biopsy Specimens.

Nicole A Cipriani, Daniel N Johnson, David H Sarne, Peter Angelos, Ward Reeves, Tatjana Antic

Abstract read
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Article in Endocrine pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicole A CiprianiDepartment of Pathology, The University of Chicago, 5841 S. Maryland Ave., MC 6101, Chicago, IL, 60637, USA. Nicole.Cipriani@uchospitals.edu.ORCID http://orcid.org/0000-0003-3092-2746
Daniel N JohnsonLittle Company of Mary Hospital, Chicago, IL, USA.
David H SarneDepartment of Medicine, Section of Endocrinology, Diabetes and Metabolism, The University of Chicago, Chicago, IL, USA.
Peter AngelosDepartment of Surgery, Section of Endocrine Surgery, The University of Chicago, Chicago, IL, USA.
Ward ReevesDepartment of Pathology, The University of Chicago, 5841 S. Maryland Ave., MC 6101, Chicago, IL, 60637, USA.
Tatjana AnticDepartment of Pathology, The University of Chicago, 5841 S. Maryland Ave., MC 6101, Chicago, IL, 60637, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In cytologically indeterminate thyroid nodules undergoing molecular testing, estimated risk of malignancy is variable. Identification of a non-cancer-specific mutation (RAS-like) confirms a neoplastic process but does not differentiate between benign, malignant, and low-risk neoplasms. This study aims to retrospectively evaluate institutional experience of Interpace (ThyGeNEXT

Indexed as

MicroRNAsThyroid NeoplasmsThyroid NoduleBiopsy, Fine-NeedleHumansProto-Oncogene Proteins B-rafRetrospective StudiesMicroRNAsProto-Oncogene Proteins B-rafFine needle aspirationMicroRNA profileMolecular testingRAS-like mutationThyroid biopsy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.