Evidence map›Paper›PMID 36227447›Full record

ArticleBiological trace element research2023

Modulation of Zinc Transporter Expressions by Additional Zinc in C2C12 Cells Cultured in a High Glucose Environment and in the Presence of Insulin or Interleukin-6.

Manuel Ruz, Mónica Andrews-Guzmán, Miguel Arredondo-Olguín

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. IL-6 Does Not Influence the Expression ofInternational journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Manuel RuzDepartment of Nutrition, Faculty of Medicine, University of Chile, Avenida Independencia 1027, Independencia, Santiago, Chile.
Mónica Andrews-GuzmánMicronutrient Laboratory, Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Macul, Santiago, Chile.
Miguel Arredondo-OlguínMicronutrient Laboratory, Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Macul, Santiago, Chile. marredon@inta.uchile.cl.
University of Chile · CL

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1120323
6 · The paper itself

Abstract

Zn status has been related to various chronic diseases presenting oxidative stress and inflammation, such as type 2 diabetes. Zn supplementation has been suggested to be a potential coadjuvant in the management of this condition. Zn transporters constitute a key component in the maintenance of Zn homeostasis. Our aim was to evaluate the modulatory effect of additional Zn (10 or 100 µM; as a ZnSO

Indexed as

Cation Transport ProteinsDiabetes Mellitus, Type 2Carrier ProteinsEndoplasmic ReticulumGlucoseHumansInsulinInterleukin-6ZincCarrier ProteinsCation Transport ProteinsGlucoseInsulinInterleukin-6Zinczinc-binding proteinGlucoseInsulinInterleukin-6ZIP transporterZnZnT transporter

Identifiers

PMID36227447
OpenAlexW4306156078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.