Evidence map›Paper›PMID 36227445›Full record

ArticleJournal of autism and developmental disorders2024

Exploring the Symptom Profiles of Intolerance of Uncertainty in Autistic Children.

Amy Keefer, Vini Singh, Yeon Sik Jang, Leigh Alon, Madison Surmacz, Calliope Holingue, Stewart H Mostofsky, Roma A Vasa

Open access · greenAbstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Amy KeeferKennedy Krieger Institute, Center for Autism and Related Disorders, Baltimore, MD, US. keefer@kennedykrieger.org.ORCID http://orcid.org/0000-0001-6931-0232
Vini SinghKennedy Krieger Institute, Center for Autism and Related Disorders, Baltimore, MD, US.
Yeon Sik JangPsychology Department, Georgetown University, Washington, DC, US.
Leigh AlonPsychology Department, Georgetown University, Washington, DC, US.
Madison SurmaczJohns Hopkins University School of Medicine, Baltimore, MD, US.
Calliope HolingueKennedy Krieger Institute, Center for Autism and Related Disorders, Baltimore, MD, US.
Stewart H MostofskyDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, US.
Roma A VasaKennedy Krieger Institute, Center for Autism and Related Disorders, Baltimore, MD, US.
Kennedy Krieger Institute · USGeorgetown University · USJohns Hopkins University · US

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
Motor Skill Learning in AutismR01NS048527 · NINDS · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MOSTOFSKY, STEWART H · 2005 to 2012
$2.9M
Somatosensory Inhibitory Dysfunction in Autism Spectrum Disorder.R01MH106564 · NIMH · JOHNS HOPKINS UNIVERSITY · PI EDDEN, RICHARD ANTHONY EDWARD · 2016 to 2020
$2.5M
NICHD NIH HHS P50 HD103538NIH HHS MH106564NIH HHS NS048527NIH HHS P50 HD103538NIMH NIH HHS R01 MH106564NINDS NIH HHS R01 NS048527
6 · The paper itself

Abstract

Intolerance of uncertainty (IU) is a multidimensional construct involving maladaptive responses to uncertainty. IU is strongly associated with autism and anxiety, yet no studies have examined its symptom profile in autistic children. This study compares IU symptom profiles in autistic and NT children and in autistic children with and without anxiety using the Intolerance of Uncertainty Scale for Children. Compared to NT peers, autistic children exhibited heightened IU symptoms in all domains, affective, behavioral, and cognitive; affective symptoms had the highest association with autism. Autistic children with anxiety also exhibited elevated IU symptoms in all domains compared to those without anxiety; behavioral IU symptoms had the highest association with anxiety. IU symptom profiles should be considered in assessment and treatment.

Indexed as

Autism Spectrum DisorderAutistic DisorderAnxietyAnxiety DisordersChildHumansUncertaintyAnxietyAutism spectrum disorderIntolerance of uncertainty

Identifiers

PMID36227445
PMCPMC10097837
OpenAlexW4304976256

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.