Evidence map›Paper›PMID 36227427›Full record

ArticleFunctional & integrative genomics2022

Basics on network theory to analyze biological systems: a hands-on outlook.

Gerardo Ruiz Amores, Agustino Martínez-Antonio

Abstract read
PubMed Publisher
In one paragraph

Article in Functional & integrative genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Clinical Proteomics Applied to Food Allergy.Advances in experimental medicine and biology · 2026
    Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gerardo Ruiz AmoresBiological Engineering Laboratory, Genetic Engineering Department, Center for Research and Advanced Studies of the National Polytechnic Institute (Cinvestav), Campus Irapuato, Km. 9.6 Libramiento Norte Carretera Irapuato-León 36821, Irapuato, Guanajuato, México.
Agustino Martínez-AntonioBiological Engineering Laboratory, Genetic Engineering Department, Center for Research and Advanced Studies of the National Polytechnic Institute (Cinvestav), Campus Irapuato, Km. 9.6 Libramiento Norte Carretera Irapuato-León 36821, Irapuato, Guanajuato, México. agustino.martinez@cinvestav.mx.ORCID http://orcid.org/0000-0003-2231-5014

Funding

CONACYT 319732
6 · The paper itself

Abstract

Biological processes result from interactions among molecules and cell-to-cell communications. In the last 50 years, network theory has empowered advances in understanding molecular networks' structure and dynamics that regulate biological systems. Adopting a network data analysis point of view at more laboratories might enrich their research capacity to generate forward working hypotheses. This work briefly describes network theory origins and provides basic graph analysis principles in biological systems, specific centrality measurements, and the main models for network structures. Also, we describe a workflow employing user-friendly free platforms to process, construct, and analyze transcriptome data from a network perspective. With this assay, we expect to encourage the implementation of network theory analysis on biological data in everyday laboratory research.

Indexed as

SoftwareTranscriptomeCytoscapeGalaxyNetwork analysisNetwork constructionTranscriptome data

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.