SynthesisInternational orthopaedics2022
Prognostic significance of frailty in older patients with hip fracture: a systematic review and meta-analysis.
Synthesis in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Prevalence and unfavorable outcome of frailty in older adults with gastric cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Pooled it
- The impact of frailty evaluation on the risk of venous thromboembolism in patients with hip fracture following surgery: a meta-analysis.Aging clinical and experimental research · 2023Pooled it
- Association Between Immediate Postoperative Pulse Pressure and Three-Year All-Cause Mortality After Hip Fracture Surgery in Older Adults: A Post Hoc Analysis of a Prospective Cohort.Journal of clinical medicine · 2026Article
- Comparing Frailty and Traditional Risk Models in Predicting 6-Month Mortality After Hip Fracture in Older Adults: A Retrospective Study from a Single Center.Journal of clinical medicine · 2026Article
- Real-world evidence of the impact of polypharmacy on mortality and recovery after hip fracture in elderly patients.Scientific reports · 2026Observational
- Article
- Integrated nutritional-inflammatory and frailty-based model for mortality risk stratification following hip fracture surgery: a multicentre cohort study.Aging clinical and experimental research · 2026Article
- Identifying frailty in acutely hospitalised patients with hip fracture: are the clinical frailty scale and irish hip fracture database frailty index comparable for predicting adverse outcomes?European geriatric medicine · 2026Article
- Ferroptosis, lipid metabolism, and genetic regulation in postoperative rehabilitation of elderly hip fractures: from molecular mechanisms to clinical translation.Frontiers in genetics · 2026Review
- Frailty and Time-To-Theatre for Elderly Hip Fracture Patients at a Regional Hospital in Australia: A Retrospective Cohort Study.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- Determinants of Length of Hospital Stay in Older Adult Hip Fracture Patients in a Northern Peruvian Hospital.Journal of clinical medicine · 2025Article
- Factors associated with frailty and the effect of frailty on postoperative outcomes in older adults with hip fracture.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- C-reactive protein -albumin-lymphocyte (CALLY) index as a predictor of early mortality in elderly patients with hip fractures.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Hip Fracture as a Systemic Disease in Older Adults: A Narrative Review on Multisystem Implications and Management.Medical sciences (Basel, Switzerland) · 2025Review
- Comorbidity burden, management, and in-hospital outcomes in centenarians with proximal hip fracture: a nationwide cohort study (2004-2020).Archives of osteoporosis · 2025Article
- Does weightbearing status impact mortality and other complications in hip fracture patients when accounting for frailty?Bone & joint open · 2025Article
- Is the continuity of the therapist-patient relationship relevant for the discharge outcome in orthopaedic physical rehabilitation?Musculoskeletal surgery · 2025Observational
- Risk Analysis Index for Estimation of 30-Day Postoperative Mortality in Hip Fractures.JAMA network open · 2025Article
- Validation of the Frail-VIG frailty index in geriatric population with femur fracture.European geriatric medicine · 2025Observational
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHip fracture (HF) has become a major healthcare concern associated with higher mortality in older patients. Frailty is one of the most important problems in aging population but its prognostic value in HF remains susceptible. This systematic review and meta-analysis aimed to evaluate the association between frailty and adverse outcomes in older patients with HF.
methodsWe systematically searched electrical databases including PubMed and Embase to find eligible literature with end-search restriction of February 20, 2021. The main endpoints were all-cause mortality, peri-operative complications, abnormal discharge, and length of stay (LOS). Pooled effect size was calculated by random-effects or fixed-effect model according to study heterogeneity. Three subgroup analyses based on follow-up times, study design, and frailty criteria were conducted.
resultsWe screened 22 studies out of 1599 identified studies in our analysis. Compared with normal patients, frail ones had a higher risk of mortality both before (OR = 3.48, 95% CI: 2.50-4.85, I
conclusionOverall, more attention needs to be paid to the prognostic effects caused by frailty in seniors with HF. Better understanding of the association between frailty and adverse outcomes in HF could help doctors perform co-management across orthopaedic and geriatric departments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.