Evidence map›Paper›PMID 36227377›Full record

ArticleEuropean journal of applied physiology2023

Acute response of biomarkers in plasma from capillary blood after a strenuous endurance exercise bout.

Thomas Reichel, Steffen Held, Anthony Schwarz, Sebastian Hacker, Fabian Wesemann, Lars Donath, Karsten Krüger

Open access · hybridAbstract read
In one paragraph

Article in European journal of applied physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thomas ReichelDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig University Giessen, Kugelberg 62, 35394, Giessen, Germany.
Steffen HeldIntervention Research in Exercise Training, German Sports University, Cologne, Germany.
Anthony SchwarzIntervention Research in Exercise Training, German Sports University, Cologne, Germany.
Sebastian HackerDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig University Giessen, Kugelberg 62, 35394, Giessen, Germany.
Fabian WesemannIntervention Research in Exercise Training, German Sports University, Cologne, Germany.
Lars DonathIntervention Research in Exercise Training, German Sports University, Cologne, Germany.
Karsten KrügerDepartment of Exercise Physiology and Sports Therapy, Institute of Sports Science, Justus-Liebig University Giessen, Kugelberg 62, 35394, Giessen, Germany. Karsten.krueger@sport.uni-giessen.de.ORCID http://orcid.org/0000-0003-1506-8254
German Sport University Cologne · DEJustus-Liebig-Universität Gießen · DE

Funding

Bundesinstitut für Sportwissenschaft 070503/20-21
6 · The paper itself

Abstract

purposeThe present study aims to investigate the acute response of potential exercise-sensitive biomarkers in capillary plasma to an acute incremental running test. In a second step, their concentration was compared to the changes in the venous serum.

methodsThirty-seven active young female and male adults completed a VO

resultsCapillary plasma concentrations of IL-1β, IL-6, IL-8, IL-17A, IFN-y, CCL-2, MMP-9, SPARC, CD163, S100A9, S100B, and BDNF increased after exercise (p < 0.05). Comparing the values from capillary plasma and venous serum, ICCs classified as good were found for IFN-y (post), while the ICCs for IL-1β, IL-8, IL-17A, CCL-2, MMP-9 (post), SPARC, and BDNF (post) were classified as moderate. For all other parameters, only weak ICCs were found.

conclusionAs in the venous serum, there was an increase in most markers in the capillary plasma. However, acceptable to low associations can be found in the concentration levels of these proteins between the compartments. Thus, this source of blood sampling could find some biomarker applications in sports practice.

Indexed as

Interleukin-6RunningAdultBiomarkersBrain-Derived Neurotrophic FactorFemaleHumansInterleukin-17Interleukin-8MaleMatrix Metalloproteinase 9OsteonectinBiomarkersBrain-Derived Neurotrophic FactorInterleukin-17Interleukin-6Interleukin-8Matrix Metalloproteinase 9OsteonectinAthletesBiomarkersEarlobe bloodPoint-of-care testingTraining monitoring

Identifiers

PMID36227377
PMCPMC9813032
OpenAlexW4304823051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.