Evidence map›Paper›PMID 36227348›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023

A deep learning approach to the diagnosis of atelectasis and attic retraction pocket in otitis media with effusion using otoscopic images.

Junbo Zeng, Wenting Deng, Jingang Yu, Lichao Xiao, Suijun Chen, Xueyuan Zhang, Linqi Zeng, Donglang Chen, Peng Li, Yubin Chen and 7 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Personalized predictive modeling of otitis media with effusion: a multivariable approach to individualized prognosis, hearing rehabilitation, and follow-up.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Observational
  2. Review
  3. Artificial intelligence in otorhinolaryngology: current trends and application areas.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Review
  4. Transforming ENT Healthcare: Advancements and Implications of Artificial Intelligence.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Junbo Zeng *Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China.
Wenting Deng *Department of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China.
Jingang Yu *School of Automation Science and Engineering, South China University of Technology, Guangzhou, China.
Lichao XiaoSchool of Automation Science and Engineering, South China University of Technology, Guangzhou, China.
Suijun ChenDepartment of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China.
Xueyuan ZhangDepartment of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China.
Linqi ZengZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Donglang ChenZhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Peng LiDepartment of Otolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Yubin ChenDepartment of Otolaryngology Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Hongzheng ZhangDepartment of Otolaryngology-Head and Neck Surgery, Zhujiang Hospital, South Medical University, Guangzhou, China.
Fan ShuDepartment of Otolaryngology-Head and Neck Surgery, Zhujiang Hospital, South Medical University, Guangzhou, China.
Minjian WuDepartment of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China.
Yuejia SuDepartment of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China.
Yuanqing LiShenshan Medical Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Shanwei, Guangdong, China.
Yuexin CaiDepartment of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China. caiyx25@mail.sysu.edu.cn.
Yiqing ZhengDepartment of Otolaryngology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107# Yanjiang West Road, Guangzhou, China. zhengyiq@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-1600-8539
Sun Yat-sen University · CNSouth China University of Technology · CNZhujiang Hospital · CN

Funding

Basic and Applied Basic Research Foundation of Guangdong Province Grant No. 2021A1515012038Guangdong Province Introduction of Innovative R&D Team Grant No. 2018B030339001National Natural Science Foundation of China Grant No. 82071062Society for the Study of Artificial Intelligence and the Simulation of Behaviour YXYGZN201904
6 · The paper itself

Abstract

backgroundThis study aimed to develop and validate a deep learning (DL) model to identify atelectasis and attic retraction pocket in cases of otitis media with effusion (OME) using multi-center otoscopic images.

methodA total of 6393 OME otoscopic images from three centers were used to develop and validate a DL model for detecting atelectasis and attic retraction pocket. A threefold random cross-validation procedure was adopted to divide the dataset into training validation sets on a patient level. A team of otologists was assigned to diagnose and characterize atelectasis and attic retraction pocket in otoscopic images. Receiver operating characteristic (ROC) curves, including area under the ROC curve (AUC), accuracy, sensitivity, and specificity were used to assess the performance of the DL model. Class Activation Mapping (CAM) illustrated the discriminative regions in the otoscopic images.

resultsAmong all OME otoscopic images, 3564 (55.74%) were identified with attic retraction pocket, and 2460 (38.48%) with atelectasis. The diagnostic DL model of attic retraction pocket and atelectasis achieved a threefold cross-validation accuracy of 89% and 79%, AUC of 0.89 and 0.87, a sensitivity of 0.93 and 0.71, and a specificity of 0.62 and 0.84, respectively. Larger and deeper cases of atelectasis and attic retraction pocket showed greater weight, based on the red color depicted in the heat map of CAM.

conclusionThe DL algorithm could be employed to identify atelectasis and attic retraction pocket in otoscopic images of OME, and as a tool to assist in the accurate diagnosis of OME.

Indexed as

Deep LearningOtitis MediaOtitis Media with EffusionPulmonary AtelectasisEar, MiddleHumansTympanic MembraneAtelectasisAttic retraction pocketDeep learningOtitis media with effusion

Identifiers

PMID36227348
PMCPMC9988777
OpenAlexW4304976079

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.