ArticleJournal of applied physiology (Bethesda, Md. : 1985)2022
Negative-pressure-assisted ventilation lowers driving pressure and mechanical power in an ARDS model.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Individualized Lung-Protective Ventilation Strategy Based on Esophageal Pressure Monitoring in Patients With ARDS Associated With Severe Acute Pancreatitis-A Randomized Controlled Trial.World journal of surgery · 2025Trial
- From physiological innovation to clinical precision: defining the right target for diaphragm neurostimulation.Journal of thoracic disease · 2026Article
- Monitoring diaphragmatic effort during diaphragm neurostimulation-assisted ventilation.Critical care (London, England) · 2025Article
- Transvenous phrenic nerve stimulation reduces diaphragm injury during controlled mechanical ventilation in a preclinical model of ARDS.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Heart-lung crosstalk in acute respiratory distress syndrome.Frontiers in physiology · 2024Review
- Phrenic nerve stimulation to prevent diaphragmatic dysfunction and ventilator-induced lung injury.Intensive care medicine experimental · 2023Review
- Phrenic Nerve Stimulation for Acute Respiratory Failure.Respiratory care · 2023Article
- Diaphragm Neurostimulation Assisted Ventilation in Critically Ill Patients.American journal of respiratory and critical care medicine · 2023Review
- Risk factors for ventilator-induced-lung injury develop three to five times faster after a single episode of lung injury.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2023Article
- Diaphragm Neurostimulation Mitigates Ventilation-Associated Brain Injury in a Preclinical Acute Respiratory Distress Syndrome Model.Critical care explorations · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Increased lung heterogeneity from regional alveolar collapse drives ventilator-induced lung injury in patients with acute respiratory distress syndrome (ARDS). New methods of preventing this injury require study. Our study objective was to determine whether the combination of temporary transvenous diaphragm neurostimulation (TTDN) with standard-of-care volume-control mode ventilation changes lung mechanics, reducing ventilator-induced lung injury risk in a preclinical ARDS model. Moderate ARDS was induced using oleic acid administered into the pulmonary artery in pigs, which were ventilated for 12 h postinjury using volume-control mode at 8 mL/kg, positive end-expiratory pressure (PEEP) 5 cmH
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.