Evidence map›Paper›PMID 36226957›Full record

ArticlemBio2022

Identification of Attenuators of Transcriptional Termination: Implications for RNA Regulation in Escherichia coli.

Teppei Morita, Nadim Majdalani, Masahiro C Miura, Rerina Inose, Taku Oshima, Masaru Tomita, Akio Kanai, Susan Gottesman

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Teppei MoritaInstitute for Advanced Biosciences, Keio Universitygrid.26091.3c, Tsuruoka, Yamagata, Japan.ORCID 0000-0001-5057-5687
Nadim MajdalaniLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Masahiro C MiuraInstitute for Advanced Biosciences, Keio Universitygrid.26091.3c, Tsuruoka, Yamagata, Japan.ORCID 0000-0001-8793-8576
Rerina InoseInstitute for Advanced Biosciences, Keio Universitygrid.26091.3c, Tsuruoka, Yamagata, Japan.
Taku OshimaDepartment of Biotechnology, Toyama Prefectural University, Imizu, Toyama, Japan.
Masaru TomitaInstitute for Advanced Biosciences, Keio Universitygrid.26091.3c, Tsuruoka, Yamagata, Japan.
Akio KanaiInstitute for Advanced Biosciences, Keio Universitygrid.26091.3c, Tsuruoka, Yamagata, Japan.ORCID 0000-0002-6362-2419
Susan GottesmanLaboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
Keio University · JPNational Cancer Institute · USToyama Prefectural University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regulatory function of many bacterial small RNAs (sRNAs) requires the binding of the RNA chaperone Hfq to the 3' portion of the sRNA intrinsic terminator, and therefore sRNA signaling might be regulated by modulating its terminator. Here, using a multicopy screen developed with the terminator of sRNA SgrS, we identified an sRNA gene (

Indexed as

Escherichia coliEscherichia coli ProteinsRNA, Small UntranslatedGene Expression Regulation, BacterialHeat-Shock ProteinsRetroviridae ProteinsRNA, BacterialcspH protein, E coliEscherichia coli ProteinsHeat-Shock ProteinsRetroviridae ProteinsRNA, BacterialRNA, Small Untranslatedcold shock proteinRhoSgrSsmall RNAtranscription termination

Identifiers

PMID36226957
PMCPMC9765468
OpenAlexW4304957748

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.