Evidence map›Paper›PMID 36226599›Full record

ArticleBiomolecules & biomedicine2023

Acquired atresia of the external auditory canal and canaloplasty with Thiersch graft reconstruction: Outcomes and complications.

Annalisa Pace, Valeria Rossetti, Giannicola Iannella, Irene Claudia Visconti, Alessandro Milani, Roberta Polimeni, Antonino Maniaci, Salvatore Cocuzza, Massimo Re, Giuseppe Magliulo

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules & biomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Annalisa PaceSense Organs Department, Sapienza University of Rome, Rome, Italy; Surgical Sciences Department, Sapienza University of Rome, Rome, Italy.
Valeria RossettiSense Organs Department, Sapienza University of Rome, Rome, Italy.
Giannicola IannellaSense Organs Department, Sapienza University of Rome, Rome, Italy.
Irene Claudia ViscontiSense Organs Department, Sapienza University of Rome, Rome, Italy.
Alessandro MilaniSense Organs Department, Sapienza University of Rome, Rome, Italy.
Roberta PolimeniSense Organs Department, Sapienza University of Rome, Rome, Italy.
Antonino ManiaciSense Organs Department, Sapienza University of Rome, Rome, Italy.
Salvatore CocuzzaOtorhinolaryngology Department, University of Catania, Catania, Italy.
Massimo ReClinical Science Department, Polytechnic University of Marche, Marche, Italy.
Giuseppe MagliuloSense Organs Department, Sapienza University of Rome, Rome, Italy.
Sapienza University of Rome · ITMarche Polytechnic University · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acquired atresia of the external auditory canal (EAC) is a rare disease characterized by otorrhea and progressive hearing loss. Clinically, it is differentiated into two stages: the wet stage and the dry stage. The dry stage does not respond to pharmacological treatment and has to be treated surgically. One surgical option is canaloplasty of the EAC with Thiersch graft reconstruction. This study aimed to report the follow-up outcomes (otomicroscopic signs and pure tone audiometry [PTA]) in patients with acquired atresia treated with this technique. Eighteen adult patients surgically treated for acquired atresia of the EAC between 2010 and 2020 were enrolled. All underwent canaloplasty with Thiersch graft reconstruction by one senior surgeon. Otomicroscopy and PTA results were evaluated before and after surgery. Postsurgical follow-up was performed at 1-3-6-12 months and then annually. Presurgical otomicroscopic examination revealed stenosis that occluded more than 75% of the EAC in all patients, and preoperative PTA showed conductive hearing loss in 89% of patients. However, postsurgical otomicroscopic examination showed that 94% of patients had a normal EAC diameter after one year, and only one patient had anterior blunting and recurrent atresia. In addition, postsurgical PTA evidenced a normal range in 89% of patients after one year. In conclusion, acquired atresia of the EAC is a troublesome disease usually associated with hearing loss. Therefore, treatment is chosen to resolve its symptoms. The results demonstrate evidence that canaloplasty with Thirsch graft may be a suitable surgical method considering the lower incidence of recurrence and the excellent hearing outcomes.

Indexed as

DeafnessHearing LossAdultAudiometry, Pure-ToneEar CanalHearingHumansTreatment Outcome

Identifiers

PMID36226599
PMCPMC9901901
OpenAlexW4304808783

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.