Evidence map›Paper›PMID 36226346›Full record

ArticleInfection & chemotherapy2022

Use of the Monoclonal Antibody Regdanvimab to Treat Patients Hospitalized with COVID-19: Real-World Data during the Delta Variant Predominance.

Yee Gyung Kwak, Je Eun Song, Jieun Kang, Jiyeon Kang, Hyung Koo Kang, Hyeon-Kyoung Koo, Hye Kyeong Park, Sang Bong Choi, Hyuk Pyo Lee, Myung Jin Lee and 1 more

Open access · goldAbstract read
In one paragraph

Article in Infection & chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yee Gyung KwakDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0002-4713-8045
Je Eun SongDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0001-7056-6905
Jieun KangDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0003-2342-0676
Jiyeon KangDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0002-3282-2952
Hyung Koo KangDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0001-9671-0944
Hyeon-Kyoung KooDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0002-1200-9892
Hye Kyeong ParkDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0002-4634-0401
Sang Bong ChoiDepartment of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-0532-3557
Hyuk Pyo LeeDepartment of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-6712-5647
Myung Jin LeeDepartment of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-8172-8025
Baek-Nam KimDepartment of Internal Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea. kimbn@paik.ac.kr.ORCID https://orcid.org/0000-0001-5551-2132
Inje University Ilsan Paik Hospital · KRInje University Sanggye Paik Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regdanvimab is the only monoclonal antibody available in Korea that targets severe acute respiratory syndrome coronavirus 2. We retrospectively evaluated the clinical characteristics of 374 adults hospitalized with coronavirus disease 2019 (COVID-19) who were treated with regdanvimab from September through December 2021. In total, 322 (86.1%) patients exhibited risk factors for disease progression. Most patients (91.4%) improved without additional treatment. No patient died or was transferred to intensive care. This study shows that regdanvimab prevented disease progression in high-risk patients with mild to moderate COVID-19 infections during Delta variant predominance.

Indexed as

COVID-19Delta variantRegdanvimab

Identifiers

PMID36226346
PMCPMC9840967
OpenAlexW4296556552

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.