Evidence map›Paper›PMID 36226228›Full record

ArticleJAC-antimicrobial resistance2022

Evaluating the long-term impact of an antimicrobial stewardship programme in a Central London mixed medical and surgical intensive care unit.

Shivani Singh, Rajiv Ark, Jason Tatlock, Sundhiya Mandalia, Christine Chung, Berge Azadian, Stephen Hughes, Nabeela Mughal, Luke S P Moore, Suveer Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JAC-antimicrobial resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shivani SinghFaculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.ORCID https://orcid.org/0000-0002-7054-1414
Rajiv ArkFaculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Jason TatlockAdult Intensive Care Unit, Chelsea and Westminster Hospital NHS Foundation Trust, 369 Fulham Road, UK.
Sundhiya MandaliaFaculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Christine ChungAdult Intensive Care Unit, Chelsea and Westminster Hospital NHS Foundation Trust, 369 Fulham Road, UK.
Berge AzadianFaculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Stephen HughesAdult Intensive Care Unit, Chelsea and Westminster Hospital NHS Foundation Trust, 369 Fulham Road, UK.
Nabeela MughalFaculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Luke S P MooreFaculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.ORCID https://orcid.org/0000-0001-7095-7922
Suveer SinghFaculty of Medicine, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.ORCID https://orcid.org/0000-0003-3219-8966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial overuse causes increased antimicrobial resistance in ICUs; antimicrobial stewardship programmes (ASPs) aim to optimize usage. Following an MDR Methods: Data were collected from ICU patients in 2008 immediately before ASP implementation, and thereafter for 6 month cohort periods in 2010-2011, 2012 and 2017. Antimicrobial usage in DDD per 1000 occupied bed days (OBD) were compared. Multivariate linear regression models for antimicrobial days were fitted, adjusting for APACHE II score and patient days. Antimicrobial resistance in Findings: Across 400 patients over 9 years, antimicrobial use changed significantly ( Conclusions: Following ASP implementation after an outbreak of MRAb, reduced antimicrobial prescribing was maintained 9 years on. We identify several factors influencing successful long-term maintenance of ASPs in ICUs.

Identifiers

PMID36226228
PMCPMC9549738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.