Evidence map›Paper›PMID 36226157›Full record

ArticleFrontiers in medicine2022

Case report: Clinical features of COVID-19 vaccine-induced exacerbation of psoriasis-A case series and mini review.

Sascha Ständer, Henner Zirpel, Florin Bujoreanu, Alin Laurentiu Tatu, Ralf J Ludwig, Diamant Thaçi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sascha StänderResearch Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany.
Henner ZirpelResearch Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany.
Florin BujoreanuDepartment of Dermatology, "Sf. Parascheva" Infectious Diseases Clinical Hospital, Galati, Romania.
Alin Laurentiu TatuDepartment of Dermatology, "Sf. Parascheva" Infectious Diseases Clinical Hospital, Galati, Romania.
Ralf J LudwigLübeck Institute of Experimental Dermatology (LIED), University of Lübeck, Lübeck, Germany.
Diamant ThaçiResearch Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany.
University of Lübeck · DEClinical Emergency Hospital Bucharest · RO"Dunarea de Jos" University of Galati · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, COVID-19 vaccination-induced exacerbation or new-onset of psoriasis have been reported. Underlying immune pathogenesis is unclear and different mechanisms are assumed. Further, clinical- and vaccine-related features and characteristics are partly inconsistent and remain to be elucidated. To add to the understanding of COVID-19 vaccination-triggered psoriasis, we report five cases with exacerbation or new-onset of psoriasis. In our cohort, one patient experienced the new onset of psoriasis, while four had an exacerbation following COVID-19 vaccination. In most patients, exacerbation or new onset occurred after the 2nd or 3rd vaccination. The mean latency from the day of vaccination was 7.2 (1.8) days (SD). The clinical impact with a mean PASI increase following COVID-19 vaccination of 7.2 (5.6) was considered relevant. In most cases, psoriatic lesions almost cleared after applying topical steroids in addition to current treatment, while one patient with psoriatic arthritis required systemic treatment. New onset and exacerbation of psoriasis have also been noted following COVID-19 infections. Hence, the underlying inflammatory response is most likely the culprit agent triggering psoriasis. This underscores that the benefits of COVID-19 vaccination far outweigh the risks, as also in patients with psoriasis.

Indexed as

COVID-19exacerbation (symptom flare up)new-onsetpsoriasisvaccination

Identifiers

PMID36226157
PMCPMC9549869
OpenAlexW4297240120

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.