Evidence map›Paper›PMID 36225938›Full record

ReviewFrontiers in immunology2022

Therapeutic strategies for gastric cancer targeting immune cells: Future directions.

Yan Zhao, Yuansong Bai, Meili Shen, Yapeng Li

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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  19. Role of lysine-specific demethylase 1 in immunotherapy of gastric cancer: An update.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yan ZhaoDepartment of Oncology and Hematology, China-Japan Union Hospital of Jilin University, Changchun, China.
Yuansong BaiDepartment of Oncology and Hematology, China-Japan Union Hospital of Jilin University, Changchun, China.
Meili ShenDepartment of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun, China.
Yapeng LiThe National and Local Joint Engineering Laboratory for Synthesis Technology of High Performance Polymer, College of Chemistry, Jilin University, Changchun, China.
Jilin University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is a malignancy with a high incidence and mortality, and the emergence of immunotherapy has brought survival benefits to GC patients. Compared with traditional therapy, immunotherapy has the advantages of durable response, long-term survival benefits, and lower toxicity. Therefore, targeted immune cells are the most promising therapeutic strategy in the field of oncology. In this review, we introduce the role and significance of each immune cell in the tumor microenvironment of GC and summarize the current landscape of immunotherapy in GC, which includes immune checkpoint inhibitors, adoptive cell therapy (ACT), dendritic cell (DC) vaccines, reduction of M2 tumor-associated macrophages (M2 TAMs), N2 tumor-associated neutrophils (N2 TANs), myeloid-derived suppressor cells (MDSCs), effector regulatory T cells (eT

Indexed as

Receptors, Chimeric AntigenStomach NeoplasmsVaccinesB7-H1 AntigenCTLA-4 AntigenHumansImmune Checkpoint InhibitorsProgrammed Cell Death 1 ReceptorTumor MicroenvironmentB7-H1 AntigenCTLA-4 AntigenImmune Checkpoint InhibitorsProgrammed Cell Death 1 ReceptorReceptors, Chimeric AntigenVaccinesgastric cancerimmune cellsimmunotherapytreatment strategytumor microenvironment

Identifiers

PMID36225938
PMCPMC9549957
OpenAlexW4296896234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.