ArticleFrontiers in immunology2022
Synthetic MRI in the detection and quantitative evaluation of sacroiliac joint lesions in axial spondyloarthritis.
Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Multi-regional radiomics of obstructive sleep apnea based on synthetic MRI.Respiratory research · 2026Article
- Diagnostic Value of T2 Mapping in Sacroiliitis Associated with Spondyloarthropathy.Diagnostics (Basel, Switzerland) · 2025Article
- Technical aspects and clinical applications of synthetic MRI: a scoping review.Diagnosis (Berlin, Germany) · 2025Article
- Automatic Image Segmentation and Grading Diagnosis of Sacroiliitis Associated with AS Using a Deep Convolutional Neural Network on CT Images.Journal of digital imaging · 2023Article
- Potential clinical feasibility of synthetic MRI in bladder tumors: a comparative study with conventional MRI.Quantitative imaging in medicine and surgery · 2023Article
- The advantages of the magnetic resonance image compilation (MAGiC) method for the prognosis of neonatal hypoglycemic encephalopathy.Frontiers in neuroscience · 2023Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
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Abstract
Objective: Our primary objective was to verify the hypothesis that synthetic magnetic resonance imaging (MRI) is similar to conventional MRI in detecting sacroiliac joint lesions in patients with axial spondyloarthritis (axSpA). A secondary objective was to assess the quantitative value of synthetic mapping in bone marrow edema (BME) and fat metaplasia. Methods: A total of 132 axSpA patients who underwent synthetic and conventional MRI from October 2019 to March 2021 were included in this prospective study. Two independent readers visually evaluated active inflammatory (BME, capsulitis, enthesitis, and inflammation at site of erosion) and structural lesions (erosion, sclerosis, ankylosis, and fat metaplasia) of the sacroiliac joints on conventional and synthetic magnetic resonance (MR) images. In addition, T1, T2, and proton density (PD) values, which were generated by synthetic mapping, were used to further quantitatively evaluate BME and fat metaplasia. A McNemar test was used to compare the differences between the two methods in the detection of sacroiliac joint lesions. Intraclass correlation coefficients (ICCs) were used to assess the inter-reader consistency of quantitative values. Mann-Whitney tests were performed, and receiver operating characteristic (ROC) curves were created for all quantitative analyses. Results: There were no statistical difference between synthetic and conventional MRI in the detection of sacroiliac joint lesions (all Conclusion: Synthetic MRI is as effective as conventional MRI in detecting sacroiliac joint lesions in patients with axSpA. Furthermore, synthetic mapping can accurately quantify BME and fat metaplasia.
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