Evidence map›Paper›PMID 36225868›Full record

ArticleFrontiers in nutrition2022

Cellular uptake, transport mechanism and anti-inflammatory effect of cyanidin-3-glucoside nanoliposomes in Caco-2/RAW 264.7 co-culture model.

Mengyu Yang, Xiaoqin Lu, Jie Xu, Xiaofeng Liu, Wei Zhang, Rongfa Guan, Hao Zhong

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Frontiers in pharmacology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengyu YangCollege of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.
Xiaoqin LuCollege of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.
Jie XuCollege of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.
Xiaofeng LiuCollege of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.
Wei ZhangCollege of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.
Rongfa GuanCollege of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.
Hao ZhongCollege of Food Science and Technology, Zhejiang University of Technology, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyanidin-3-glucoside (C3G), which is the widest and richest anthocyanin (ACN) found in the edible fruit and vegetables, has been illustrated to perform a wide range of bioactivities. Nanoliposomes can inhibit C3G degradation and enhance the absorption rate of C3G as tools for conveying materials to particular locations. This experiment aims to study the absorption, transport and anti-inflammatory effects of C3G nanoliposomes in Caco-2/RAW 264.7 co-culture model, which symbolizes an intestinal inflammation system. The results indicated that the uptake and transport of C3G nanoliposomes by Caco-2/RAW 264.7 co-culture model were concentration-dependent as well as affected by temperature (37 and 4°C) and endocytic inhibitors, which revealed C3G nanoliposomes penetrate cells

Indexed as

anti-inflammationco-culturecyanidin-3-glucosidetransportuptake

Identifiers

PMID36225868
PMCPMC9549275

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.