Evidence map›Paper›PMID 36225745›Full record

ArticleOpen forum infectious diseases2022

PrEP Indications and PrEP Knowledge, Access, and Interest Among Individuals With HCV.

Kristi C Hill, Sarah M Kattakuzhy, Rachel Silk, Rahwa Eyasu, Onyinyechi Ogbumbadiugha, Emade Ebah, Amelia A Cover, Ashley Davis, Britt Gayle, David Sternberg and 6 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Kristi C HillHarvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8078-9667
Sarah M KattakuzhyUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Rachel SilkUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Rahwa EyasuUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Onyinyechi OgbumbadiughaUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Emade EbahUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Amelia A CoverUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Ashley DavisUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Britt GayleUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
David SternbergHIPS, Washington DC, USA.
Phyllis BijoleHIPS, Washington DC, USA.
Junfeng SunNational Institutes of Health, Bethesda, Maryland, USA.
Henry MasurNational Institutes of Health, Bethesda, Maryland, USA.
Shyam KottililUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Daniel SolomonHarvard Medical School, Boston, Massachusetts, USA.
Elana S RosenthalUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
University of Maryland, Baltimore · USHarvard University · USNational Institutes of Health · US

Funding

CLC NIH HHS HHSN269201400012C
6 · The paper itself

Abstract

Background: Individuals with hepatitis C (HCV) represent a population that may benefit from pre-exposure prophylaxis (PrEP), given the overlapping risk factors and transmission networks of HCV and HIV. This analysis assesses the prevalence of PrEP indications among individuals with HCV monoinfection and PrEP awareness, interest, and access in this population. Methods: GRAVITY was an observational study for the collection of epidemiologic data from individuals with HCV and/or HIV in Washington DC and Baltimore, with the present analysis limited to HCV-monoinfected patients. The prevalence of PrEP indications was determined using epidemiologic survey responses. Bivariate and multivariable analyses assessed for associations between PrEP indications and PrEP awareness, access, and interest. Results: Among 314 HCV-monoinfected participants, 109 (35%) had an indication for PrEP. Forty-eight (44%) had a drug use indication alone, 40 (37%) had a sexual indication alone, and 21 (19%) had both drug use and sexual indications. Eighty-five (27%) participants had heard of PrEP, 32 (10%) had been offered PrEP by a provider, 114 (38%) were interested or maybe interested in PrEP, and 6 (2%) were currently taking PrEP. On bivariate analysis, PrEP awareness was significantly associated with study site ( Conclusions: Though indications for PrEP were prevalent among individuals with HCV in this cohort, most patients were unaware of PrEP, had never been offered PrEP, and were not using PrEP. These data support the need for improved PrEP implementation among people with HCV.

Indexed as

HCVhepatitis CHIVHIV preventionpeople who inject drugspre-exposure prophylaxisPrEPPWID

Identifiers

PMID36225745
PMCPMC9547499
OpenAlexW4295763120

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.