Evidence map›Paper›PMID 36225733›Full record

ArticleFrontiers in neuroscience2022

Non-invasive diagnosis and monitoring tool of children's mental health: A point-of-care immunosensor for IL-6 quantification in saliva samples.

Andrea Cruz, Maria Vieira, Ana R Mesquita, Adriana Sampaio, Inês Mendes-Pinto, Isabel Soares, Paulo P Freitas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Andrea CruzProChild CoLAB Against Child Poverty and Social Exclusion, Portuguese Foundation for Science and Technology (FCT) Collaborative Laboratory, Guimarães, Portugal.
Maria VieiraInternational Iberian Nanotechnology Laboratory, Braga, Portugal.
Ana R MesquitaCIPsi, School of Psychology, University of Minho, Braga, Portugal.
Adriana SampaioCIPsi, School of Psychology, University of Minho, Braga, Portugal.
Inês Mendes-PintoInternational Iberian Nanotechnology Laboratory, Braga, Portugal.
Isabel SoaresCIPsi, School of Psychology, University of Minho, Braga, Portugal.
Paulo P FreitasInternational Iberian Nanotechnology Laboratory, Braga, Portugal.
International Iberian Nanotechnology Laboratory · PTUniversity of Minho · PTFundação para a Ciência e Tecnologia · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mental disorders are commonly featured as chronic conditions with often onset during childhood. In this context, inflammation has been associated with a higher risk of developing physical and mental health problems. Interleukin (IL)-6 is a key mediator of inflammatory responses and plays a pivotal role in immune and nervous system interaction. High levels of IL-6 during childhood are associated with mental problems, indicating that the IL-6 molecular pathway may represent a new target for monitoring and treating these conditions. Here, we report the detection of IL-6 in saliva samples from children (

Indexed as

childrenIL-6immunosensormental healthpoint-of-caresaliva

Identifiers

PMID36225733
PMCPMC9549322
OpenAlexW4297226979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.