Evidence map›Paper›PMID 36225538›Full record

ArticleFrontiers in clinical diabetes and healthcare2022

Unpacking determinants and consequences of food insecurity for insulin resistance among people living with HIV: Conceptual framework and protocol for the NOURISH-OK study.

Marianna S Wetherill, Casey Bakhsh, Lacey Caywood, Mary B Williams, Micah L Hartwell, Denna L Wheeler, Randolph D Hubach, T Kent Teague, Gerwald Köhler, James R Hebert and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in clinical diabetes and healthcare, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Food is Medicine Initiative for Mitigating Food Insecurity in the United States.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2024
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Marianna S WetherillDepartment of Health Promotion Sciences, Hudson College of Public Health, University of Oklahoma Tulsa Schusterman Center, Tulsa, OK, United States.
Casey BakhshTulsa CARES, Tulsa, OK, United States.
Lacey CaywoodDepartment of Health Promotion Sciences, Hudson College of Public Health, University of Oklahoma Tulsa Schusterman Center, Tulsa, OK, United States.
Mary B WilliamsDepartment of Family and Community Medicine, University of Oklahoma School of Community Medicine, Tulsa, OK, United States.
Micah L HartwellDepartment of Psychiatry, Oklahoma State University Center for Health Sciences, Tulsa, OK, United States.
Denna L WheelerCenter for Rural Health, Oklahoma State University Center for Health Sciences, Tulsa, OK, United States.
Randolph D HubachDepartment of Public Health, Purdue University, West Lafayette, IN, United States.
T Kent TeagueDepartment of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, United States.
Gerwald KöhlerDepartment of Biochemistry and Microbiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, United States.
James R HebertDepartment of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC, United States.
Sheri D WeiserDivision of HIV, Infectious Disease and Global Medicine, Department of Medicine, University of California, San Francisco (UCSF), San Francisco, CA, United States.
Oklahoma State University Center for Health Sciences · USUniversity of Oklahoma · USPurdue University West Lafayette · USTulsa City-County Library · USTulsa Community College · USUniversity of California, San Francisco · USUniversity of South Carolina · US

Funding

Tracking and Evaluation CoreU54GM104938 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI JUDITH A JAMES · 2013 to 2026
$68.2M
Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma (NOURISH OK) - Administrative SupplementR01DK127464 · NIDDK · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WETHERILL, MARIANNA · 2020 to 2024
$2.6M
NIDDK NIH HHS R01 DK127464NIGMS NIH HHS U54 GM104938
6 · The paper itself

Abstract

Background: Over the past four decades, advances in HIV treatment have contributed to a longer life expectancy for people living with HIV (PLWH). With these gains, the prevention and management of chronic co-morbidities, such as diabetes, are now central medical care goals for this population. In the United States, food insecurity disproportionately impacts PLWH and may play a role in the development of insulin resistance through direct and indirect pathways. The Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma (NOURISH-OK) will use a novel, multi-level, integrated framework to explore how food insecurity contributes to insulin resistance among PLWH. Specifically, it will explore how food insecurity may operate as an intermediary risk factor for insulin resistance, including potential linkages between upstream determinants of health and downstream consequences of poor diet, other behavioral risk factors, and chronic inflammation. Methods/design: This paper summarizes the protocol for the first aim of the NOURISH-OK study, which involves purposeful cross-sectional sampling of PLWH (n=500) across four levels of food insecurity to test our conceptual framework. Developed in collaboration with community stakeholders, this initial phase involves the collection of anthropometrics, fasting blood samples, non-blood biomarkers, 24-hour food recall to estimate the Dietary Inflammatory Index (DII Discussion: The NOURISH-OK study will address important research gaps to inform the development of food as medicine interventions to support healthy aging for PLWH.

Indexed as

community-based participatory research (CBPR)food accessfood insecurityHIV- human immunodeficiency virusinflammationinsulin resistancemicrobiomestructural equation modeling

Identifiers

PMID36225538
PMCPMC9552993
OpenAlexW4293498746

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.