Evidence map›Paper›PMID 36225513›Full record

ArticleCureus2022

Hypokalemic Periodic Paralysis Exacerbated by Carbohydrate Load: A Case Report.

Ryan Blanton, Safi Afzal

Abstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Permanent weakness and myopathy in hypokalemic periodic paralysis.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2026
    Review
  2. Article
  3. Thyrotoxic Hypokalemic Periodic Paralysis: Pathophysiological Mechanisms.Endocrinology and metabolism (Seoul, Korea) · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ryan BlantonEmergency Medicine, Campbell University School of Osteopathic Medicine, Lillington, USA.
Safi AfzalInternal Medicine, Cape Fear Valley Medical Center, Fayetteville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 35-year-old male presented with weakness in all four extremities rendering him unable to ambulate. The patient stated the symptoms began after consuming an unknown, large amount of Oreo cookies; thus, a high carbohydrate load likely caused him to exceed the recommended dietary allowance (RDA) of 225-325 grams of carbohydrates per day, depending on one's daily caloric intake. Lab workup revealed a potassium level of 2.1 mmol/L. Upon potassium replacement, the patient's symptoms improved to baseline, and he was discharged home with follow-up instructions that included a referral for genetic testing. Hypokalemic periodic paralysis (HPP) is a rare condition that, despite having a relatively simple solution for treatment, can lead to an extensive and expensive workup if not considered early on the list of differential diagnoses. Herein, we will discuss the pathophysiology, clinical signs/symptoms, and management of HPP.

Indexed as

carbohydrate loaddiethypokalemiahypokalemic periodic paralysisinsulinmagnesiumna-k atpasepotassium

Identifiers

PMID36225513
PMCPMC9536358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.