Evidence map›Paper›PMID 36225335›Full record

ArticleERJ open research2022

Evaluation of aerosol drug delivery with concurrent low- and high-flow nasal oxygen.

Barry Murphy, Marc Mac Giolla Eain, Mary Joyce, James B Fink, Ronan MacLoughlin

Abstract read
In one paragraph

Article in ERJ open research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Barry MurphyResearch and Development, Science & Emerging Technologies, Aerogen Limited, Galway, Ireland.ORCID https://orcid.org/0000-0002-2833-1229
Marc Mac Giolla EainResearch and Development, Science & Emerging Technologies, Aerogen Limited, Galway, Ireland.ORCID https://orcid.org/0000-0002-0211-2132
Mary JoyceResearch and Development, Science & Emerging Technologies, Aerogen Limited, Galway, Ireland.ORCID https://orcid.org/0000-0002-2035-0687
James B FinkAerogen Pharma Corporation, San Mateo, CA, USA.ORCID https://orcid.org/0000-0001-6527-2363
Ronan MacLoughlinResearch and Development, Science & Emerging Technologies, Aerogen Limited, Galway, Ireland.ORCID https://orcid.org/0000-0002-3164-1607

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Question addressed by study: Administration of aerosol to patients receiving high-flow nasal oxygen (HFNO) ranges from concurrent aerosol delivery by mouthpiece to aerosol Materials and methods: A vibrating mesh nebuliser delivered salbutamol Results: Concurrent low-flow nasal oxygen (LFNO) and aerosol delivery with a mouthpiece and aerosol holding chamber increased the inhaled dose (%) available, 31.44±1.33% when supplemented with 2 L·min Answer to question posed: Concurrent LFNO with a mouthpiece and aerosol holding chamber is an effective and safe means of aerosol delivery.

Identifiers

PMID36225335
PMCPMC9549318

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.