Evidence map›Paper›PMID 36225198›Full record

ArticleDisease markers2022

Rosiglitazone Alleviates Contrast-Induced Acute Kidney Injury in Rats via the PPAR

Jiayi Wu, Jinhua Huang, En Chen, Xingchun Zheng

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Implication of MAPK, Lipocalin-2, and Fas in the protective action of liposomal resveratrol against isoproterenol-induced kidney injury.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  4. Research progress on animal models of contrast-induced acute kidney injury.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiayi WuDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, 350001 Fujian, China.
Jinhua HuangDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, 350001 Fujian, China.
En ChenDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, 350001 Fujian, China.
Xingchun ZhengDepartment of Cardiology, Fujian Medical University Union Hospital, Fuzhou, 350001 Fujian, China.ORCID https://orcid.org/0000-0003-2937-5896
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study investigated the effect and mechanism of rosiglitazone on a rat model with contrast-induced acute kidney injury (CI-AKI). Materials and Methods: The CI-AKI rat model was established from Sprague Dawley rats by furosemide injection (10 ml/kg) to the caudal vein followed by iohexol (11.7 ml/kg). The experimental grouping was randomly allocated into control, model, rosiglitazone, and T0070907 groups. Blood samples were collected from the abdominal aorta. Serum creatinine, urea nitrogen, MDA, and SOD contents were detected by biochemical analysis. TNF- Results: The CI-AKI rat model was successfully established because the results showed that compared with control, serum creatinine, urea nitrogen, MDA, SOD, TNF- Conclusion: Rosiglitazone could alleviate acute renal injury in the CI-AKI rat model by regulating the PPAR

Indexed as

Acute Kidney InjuryRosiglitazoneAnimalsCaspase 3CreatinineFurosemideInterleukin-10IohexolKidneyNitrogenNLR Family, Pyrin Domain-Containing 3 ProteinPPAR gammaRatsRats, Sprague-DawleyRNA, MessengerSignal TransductionCaspase 3CreatinineFurosemideInterleukin-10IohexolNitrogenNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, ratPPAR gammaRNA, MessengerRosiglitazoneSuperoxide DismutaseTumor Necrosis Factor-alphaUrea

Identifiers

PMID36225198
PMCPMC9550500
OpenAlexW4300817261

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.