Evidence map›Paper›PMID 36225153›Full record

ArticleJournal of the International AIDS Society2022

An evaluation of nine culturally tailored interventions designed to enhance engagement in HIV care among transgender women of colour in the United States.

Gregory M Rebchook, Deepalika Chakravarty, Jessica M Xavier, JoAnne G Keatley, Andres Maiorana, Jae Sevelius, Starley B Shade, SPNS Transgender Women of Color Study Group

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gregory M RebchookDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California, USA.ORCID 0000-0002-7778-9041
Deepalika ChakravartyDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California, USA.
Jessica M XavierIndependent Consultant, Silver Spring, Maryland, USA.
JoAnne G KeatleyDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California, USA.
Andres MaioranaDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California, USA.
Jae SeveliusDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California, USA.
Starley B ShadeDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California, USA.
SPNS Transgender Women of Color Study GroupDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California, USA.
University of California, San Francisco · US

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Monica Gandhi · 1988 to 2026
$93.6M
Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
Mentoring clinical investigators in patient-oriented research on substance use and HIVK24DA051328 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEVELIUS, JAE M. · 2020 to 2024
$771k
HRSA HHS U90HA24973NIAID NIH HHS P30 AI027763NIDA NIH HHS K24 DA051328NIH HHS P30 AI027763NIMH NIH HHS P30 MH062246
6 · The paper itself

Abstract

introductionTransgender women (TW) worldwide have a high prevalence of HIV, and TW with HIV encounter numerous healthcare barriers. It is critical to develop evidence-informed interventions to improve their engagement in healthcare to achieve durable viral suppression (VS). We evaluated whether participation in one of nine interventions designed specifically for TW was associated with improved engagement in HIV care among transgender women of colour (TWC).

methodsBetween 2013 and 2017, nine US organizations implemented nine distinct and innovative HIV care engagement interventions with diverse strategies, including: individual and group sessions, case management and navigation, outreach, drop-in spaces, peer support and/or incentives to engage TWC with HIV in care. The organizations enrolled 858 TWC, conducted surveys, captured intervention exposure data and extracted medical record data. Our evaluation of the interventions employed a pre-post design and examined four outcomes-any HIV care visit, antiretroviral therapy (ART) prescription, retention in HIV care and VS (both overall and among those with a clinic visit and viral load test), at baseline and every 6 months for 24 months. We employed logistic generalized estimating equations to assess the relative odds of each outcome at 12 and 24 months compared to baseline.

resultsOverall, 79% of participants were exposed to at least one intervention activity. Over 24 months of follow-up, participants received services for a median of over 6 hours (range: 3-69 hours/participant). Compared to baseline, significantly (p<0.05) greater odds were demonstrated at both 12 and 24 months for three outcomes: prescription of ART (ORs: 1.42 at 12 months, 1.49 at 24 months), VS among all participants (ORs: 1.49, 1.54) and VS among those with a clinic visit and viral load test (ORs: 1.53, 1.98). The outcomes of any HIV care visit and retention in HIV care had significantly greater odds (ORs: 1.38 and 1.58, respectively) only at 12 months compared to baseline.

conclusionsThese evaluation results illustrate promising approaches to improve engagement in HIV care and VS among TWC with HIV. Continued development, adaptation and scale-up of culturally tailored HIV care interventions for this key population are necessary to meet the UNAIDS 95-95-95 goals.

Indexed as

HIV InfectionsTransgender PersonsAnti-Retroviral AgentsElectrolytesFemaleHumansMaleSkin PigmentationUnited StatesAnti-Retroviral AgentsElectrolytesacquired immunodeficiency syndromecontinuity of patient caredelivery of healthcareevidence-informed interventionsHIV infectionstransgender persons

Identifiers

PMID36225153
PMCPMC9557010
OpenAlexW4304822802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.