Evidence map›Paper›PMID 36225121›Full record

ArticleBrain and behavior2022

Characterization of meningiomas with synthetic imaging.

Riccardo Ludovichetti, Bénédicte Delattre, José Boto, Daniela LaGrange, Torstein Meling, Maria Isabel Vargas

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Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Riccardo LudovichettiDivision of Radiology, Diagnostic Department, Geneva University Hospitals, Geneva, Switzerland.
Bénédicte DelattreDivision of Radiology, Diagnostic Department, Geneva University Hospitals, Geneva, Switzerland.
José BotoDivision of Neuroradiology, Diagnostic Department, Geneva University Hospitals, Geneva, Switzerland.
Daniela LaGrangeDivision of Neuroradiology, Diagnostic Department, Geneva University Hospitals, Geneva, Switzerland.
Torstein MelingDivision of Neurosurgery, Neurosciences Department, Geneva University Hospitals, Geneva, Switzerland.
Maria Isabel VargasDivision of Neuroradiology, Diagnostic Department, Geneva University Hospitals, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSynthetic magnetic resonance imaging (SyMRI) is a novel quantitative and qualitative technique that permits the reconstruction of multiple image contrasts and quantitative maps from a single scan, thereby providing quantitative information and reducing scan times. The purpose of this study is to characterize intracranial meningiomas using SyMRI.

methodsThe study included 35 patients with meningiomas (6 males, 29 females; mean age 61 ± 17 years; range 21-90 years). Using 3T MR scanners, SyMRI was performed in addition to conventional FSET2, FLAIR, DWI, T1, and T1 with gadolinium. SyMRI software was used to generate T1, T2, and PD quantitative maps. Osirix MD was used to measure quantitative values of T1, T2, and PD using a ROI.

resultsWe analyzed 42 meningiomas, 8 of which were associated with edema, and 5 contained calcifications. Mean relaxivity values of meningiomas on synthetic T1, T2, and PD maps at 3T MRI were 1382.6 ± 391.7 ms, 95.6 ± 36.5 ms, and 89.1 ± 9.7 pu, respectively. Signal intensities in terms of T1, T2, and PD did not differ significantly between meningiomas with and without edema (p = .994, p = .356, and p = .221, respectively), nor between meningiomas containing and not containing calcifications (p = .840, p = .710, and p = .455, respectively). Values of T1 and T2 measured in meningiomas and the normal-appearing white matter approximated reference values found in the literature with other quantitative methods.

conclusionThe presented method offers a novel approach to characterize meningiomas through their relaxation parameters measured with a SyMRI sequence.

Indexed as

Meningeal NeoplasmsMeningiomaAdultAgedBrainContrast MediaFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedContrast MediabiomarkersmeningiomasMRIrelaxivity valuessynthetic imaging

Identifiers

PMID36225121
PMCPMC9660428

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.