Evidence map›Paper›PMID 36224762›Full record

ArticleThe Journal of international medical research2022

Correlations between serum hepatitis B core-related antigen and hepatitis B surface antigen in patients with hepatitis B cirrhosis and a hepatitis B virus-DNA-negative status: a retrospective study.

Baiguo Xu, Anjing Liu, Ying Liu, Tao Han, Hua Guo, Xian Ding, Huiling Xiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Baiguo XuDepartment of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University, Tianjin, China; Tianjin Institute of Hepatobiliary Disease, Tianjin, China.ORCID 0000-0002-0269-5155
Anjing LiuCenter of Infectious Diseases, Tanggu Infectious Disease Hospital of Tianjin, Tianjin, China.
Ying LiuDepartment of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University, Tianjin, China; Tianjin Institute of Hepatobiliary Disease, Tianjin, China.
Tao HanDepartment of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University, Tianjin, China; Tianjin Institute of Hepatobiliary Disease, Tianjin, China.
Hua GuoInstitute of Hepatobiliary Disease of Tianjin, Tianjin, China; The Third Central Hospital of Tianjin, Tianjin, China.
Xian DingDepartment of Clinical Laboratory, The Third Central Hospital of Tianjin, Tianjin, China; Institute of Hepatobiliary Disease of Tianjin, Tianjin, China.
Huiling XiangDepartment of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University, Tianjin, China; Tianjin Institute of Hepatobiliary Disease, Tianjin, China.
Tianjin Fire Research Institute · CNTianjin Third Central Hospital · CNTianjin Infectious Diseases Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to examine the correlations between serum hepatitis B core-related antigen (HBcrAg) and hepatitis B surface antigen (HBsAg) titers in patients with hepatitis B cirrhosis and a hepatitis B virus (HBV)-DNA-negative status.

methodsWe retrospectively analyzed the data and blood samples of patients who were diagnosed with HBV liver cirrhosis and an HBV-DNA negative status. These patients were hospitalized between October 2018 and October 2019 at one hospital.

resultsA total of 180 patients were included. The median (interquartile range) HBsAg and HBcrAg concentrations were 2.77 log

conclusionsThere might be a non-linear relationship between HBcrAg and HBsAg concentrations in patients with hepatitis B cirrhosis and an HBV-DNA-negative status.

Indexed as

Hepatitis BHepatitis B, ChronicBiomarkersDNA, ViralHepatitis B Core AntigensHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHumansLiver CirrhosisRetrospective StudiesBiomarkersDNA, ViralHepatitis B Core AntigensHepatitis B e AntigensHepatitis B Surface AntigensHBV-DNA-negativeHepatitis B cirrhosishepatitis B core-related antigenhepatitis B surface antigenliverserological marker

Identifiers

PMID36224762
PMCPMC9561681
OpenAlexW4304805779

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.