SynthesisCancer medicine2023
Fertility discussions and concerns in childhood cancer survivors, a systematic review for updated practice.
Synthesis in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Mapping and comparing the quality of life outcomes in childhood and adolescent and young adult cancer survivors: an umbrella review and future directions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Pooled it
- Fertility discussions and concerns in childhood cancer survivors, a systematic review for updated practice.Cancer medicine · 2023Pooled it
- Fertility Preservation Discussions And Decisions: Results From a Pilot Randomized Controlled Trial Among Adolescent Males With Cancer.Pediatric blood & cancer · 2025Trial
- Infertility costs and associated factors in childhood cancer survivors: the role of radiotherapy.Journal of cancer survivorship : research and practice · 2026Article
- Experience in the approach to adolescents with cancer in a multidisciplinary unit. Growing together.European journal of pediatrics · 2026Article
- Human iPSCs derived from cryopreserved testicular somatic cells enable germline regeneration in childhood cancer survivors.Human reproduction open · 2026Article
- Beyond Survival: Addressing Pediatric Oncofertility Risk, Preservation Methods, and Care Disparities.Pediatric annals · 2025Review
- From Survival to Parenthood: The Fertility Journey After Childhood Cancer.Biomedicines · 2025Review
- Sleeping Spermatozoa: The Symbolism of Gamete Cryopreservation in the Context of Cancer in AYAs.Life (Basel, Switzerland) · 2025Article
- Inequalities in Fertility-Impacting Cancer Incidence Among Young Populations in the United States.Cancer medicine · 2025Article
- Controlled ovarian stimulation for oocyte preservation in childhood cancer survivors who have undergone chemotherapy.Human reproduction open · 2025Article
- Fertility preservation methods in children with the risk of female hypogonadism - possibilities and limitations.Pediatric endocrinology, diabetes, and metabolism · 2025Review
- Fertility-Related Concerns in Long-Term Survivors of Childhood Cancer: A Canadian Cohort Study.Current oncology (Toronto, Ont.) · 2024Article
- Article
- Current Status of Fertility Preservation in Pediatric Oncology Patients.Children (Basel, Switzerland) · 2024Review
- Ethical, legal, social, and policy issues of ovarian tissue cryopreservation in prepubertal girls: a critical interpretive review.Journal of assisted reproduction and genetics · 2024Review
- Update and new advances in fertility preservation and cancer.CA: a cancer journal for cliniciansReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo provide ways to improve the clinical practice of fertility preservation (FP) for children, adolescents, and young adults (AYA) with cancer.
designA systematic research of online databases was undertaken in March 2020 following the PRISMA criteria, including Medline and Web of Science.
resultsFifty-nine articles were included. Surveys, interviews, and focus groups were used to collect data from patients, parents, and health care providers (HCPs). Four themes worth exploring emerged: (a) what do patients and professionals think of and know about FP? (b) what makes the fertility discussion happen or not? (c) what, retrospectively, led to FP being pursued or not? and (d) how do patients and HCPs feel about fertility issues?
conclusionA minority of AYAs preserve their fertility (banking assay for 45% of boys and 23% of girls). Yet fertility concerns have a significant impact on the quality of life of young cancer survivors. Although recommendations and guidelines regarding FP are available internationally, there are no specific guidelines as to how to conduct fertility counseling for children and adolescents. Some barriers are not removable, such as a poor prognosis of an obvious severe disease, time constraints for starting treatment, and cultural and religious beliefs. In response to aspects hindering patients and families to be receptive to any discussion at the time of diagnosis, psychological support could reduce the level of emotional distress and help restore a degree of open-mindedness to open a window for discussion. Moreover, as the lack of knowledge of professionals about fertility is frequently pointed out as a limiting factor for fertility discussion, reinforcing professional training regarding FP could be proposed to promote fertility discussion and eventually referral for FP.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.