Evidence map›Paper›PMID 36224709›Full record

ArticleResearch report (Health Effects Institute)2022

Mortality-Air Pollution Associations in Low Exposure Environments (MAPLE): Phase 2.

M Brauer, J R Brook, T Christidis, Y Chu, D L Crouse, A Erickson, P Hystad, C Li, R V Martin, J Meng and 7 more

Abstract read
In one paragraph

Article in Research report (Health Effects Institute), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Effects of the inhaled dose of air pollution on health: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Long-Term Exposure to Low-LevelEnvironmental health perspectives · 2023
    Pooled it
  3. Review
  4. Prescribed fire is unlikely to reduce net PMProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Differential Reductions in Total and Compositional PMEnvironmental science & technology · 2026
    Article
  11. Ambient PMEnvironment & health (Washington, D.C.) · 2026
    Article
  12. Observational
  13. Burden of disease attributable to PMEnvironmental health : a global access science source · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Long-term exposure to ambient PMEnvironmental epidemiology (Philadelphia, Pa.) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

M BrauerThe University of British Columbia, Vancouver, British Columbia, Canada.
J R BrookUniversity of Toronto, Toronto, Ontario, Canada.
T ChristidisHealth Analysis Division, Statistics Canada, Ottawa, Ontario, Canada.
Y ChuThe University of British Columbia, Vancouver, British Columbia, Canada.
D L CrouseUniversity of New Brunswick, Fredericton, New Brunswick, Canada.
A EricksonThe University of British Columbia, Vancouver, British Columbia, Canada.
P HystadOregon State University, Corvallis, Oregon.
C LiDalhousie University, Halifax, Nova Scotia, Canada.
R V MartinDalhousie University, Halifax, Nova Scotia, Canada.
J MengDalhousie University, Halifax, Nova Scotia, Canada.
A J PappinHealth Analysis Division, Statistics Canada, Ottawa, Ontario, Canada.
L L PinaultHealth Analysis Division, Statistics Canada, Ottawa, Ontario, Canada.
M TjepkemaHealth Analysis Division, Statistics Canada, Ottawa, Ontario, Canada.
A van DonkelaarDalhousie University, Halifax, Nova Scotia, Canada.
C WeagleDalhousie University, Halifax, Nova Scotia, Canada.
S WeichenthalMcGill University, Montreal, Quebec, Canada.
R T BurnettPopulation Studies Division, Health Canada, Ottawa, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMortality is associated with long-term exposure to fine particulate matter (particulate matter ≤2.5 μm in aerodynamic diameter; PM

methodsPM Annual exposures to PM In addition to linear models, the shape of the concentration-response function was investigated using restricted cubic splines (RCS). The number of knots were selected by minimizing the Bayesian Information Criterion (BIC). Two additional models were used to examine the association between nonaccidental mortality and PM Sensitivity analyses were conducted to examine associations between PM

resultsThe refined PM Positive associations between outdoor PM In the mCCHS cohort analyses inclusion of behavioral covariates did not substantially change the results for both linear and nonlinear models. We examined the sensitivity of the shape of the nonaccidental mortality-PM Among the other causes of death examined, PM In sensitivity analyses, the addition of O

conclusionsIn several large, national Canadian cohorts, including a cohort of 7.1 million unique census respondents, associations were observed between exposure to PM

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureMortalityAdultAgedAged, 80 and overBayes TheoremCanadaHumansMiddle AgedNitrogen DioxideOxidantsOzoneParticulate MatterAir PollutantsNitrogen DioxideOxidantsOzoneParticulate Matter

Identifiers

PMID36224709
PMCPMC9556709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.