Evidence map›Paper›PMID 36224673›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2022

[Mechanism of miRNA-3679 Inhibiting Downstream ZADH2-Target Genes to Promote Hepatocellular Carcinoma Cell Proliferation].

Jing-Yu He, Xue-Qin Zhou, Wen-Tao Wang

Open access · greenAbstract read
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  2. [miR-342-3p Promotes the Proliferation, Migration, and Invasion of Clear Cell Renal Cell Carcinoma Cells by Targeted Inhibition of PPM1E].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jing-Yu HeDepartment of Liver Surgery,West China Hospital, Sichuan University, Chengdu 610041, China.
Xue-Qin ZhouDepartment of Hepatobiliary and Pancreatic Surgery, the Third Hospital of Mianyang and Sichuan Mental Health Center, Mianyang 621000, China.
Wen-Tao WangDepartment of Liver Surgery,West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan University · CNMianyang Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine the relationship between miRNA-3679 and hepatocellular carcinoma (HCC) cell lines, and to verify the downstream target genes of miRNA-3679. Methods: PCR was used to determine the expression of miRNA-3679 in liver cancer cell lines, and databases, including ENCORI, miRDB and TargetScan, were used to predict the downstream target genes of miRNA-3679. qPCR of the normal control group (or NC group), miR-3679 inhibitor group and transfection negative control group (or inhibitor NC group) was done to determine the transfection efficiency of the target gene, thereby identifying zinc-binding alcohol dehydrogenase domain containing 2 ( Results: The expression level of miRNA-3679 in HCC cell lines was higher than that in normal human liver cell lines ( Conclusion: miRNA-3679 is significantly highly expressed in HCC cells and miRNA-3679 can directly interact with

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsAlcohol DehydrogenaseAntigens, SurfaceApoptosisCell LineCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansLuciferasesZincAlcohol DehydrogenaseAntigens, SurfaceLuciferasesMicroRNAsZADH2 protein, humanZincHCCMicro-ribonucleic acidMicro-ribonucleic acid-3679Plasticity-related gene 3Zinc-binding alcohol dehydrogenase domain containing 2

Identifiers

PMID36224673
PMCPMC10408807
OpenAlexW4306168036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.