Evidence map›Paper›PMID 36224613›Full record

ArticleJournal of orthopaedic surgery and research2022

SPECT/CT imaging features of cystic degeneration of the talus and their relation to pathological findings.

Qitao Song, Xiantie Zeng, Haijing Huang, Lei Long, Jin Xu, Shuangshuang Cui, Zhonghai Li, Xinlong Ma

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Qitao SongDepartment of Nuclear Medicine, Tianjin Hospital, Tianjin, People's Republic of China.
Xiantie ZengDepartment of Traumatology, Tianjin Hospital, Tianjin, People's Republic of China.
Haijing HuangDepartment of Traumatology, Tianjin Hospital, Tianjin, People's Republic of China.
Lei LongDepartment of Nuclear Medicine, Tianjin Hospital, Tianjin, People's Republic of China.
Jin XuDepartment of Pathology, Tianjin Hospital, Tianjin, People's Republic of China.
Shuangshuang CuiDepartment of Traumatology, Tianjin Hospital, Tianjin, People's Republic of China.
Zhonghai LiDepartment of Orthopaedics, First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China. lizhonghaispine@126.com.
Xinlong MaDepartment of Traumatology, Tianjin Hospital, Tianjin, People's Republic of China. fqyd2022@163.com.
Tianjin Hospital · CNTianjin People's Hospital · CNFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteochondral lesions of the talus (OLTs) are a common orthopedic condition. The image presentation is very similar to that of ischemic necrosis of the talus complicated by a talar neck fracture, but the two are very different lesions. When abnormalities in bone density (or signal) of the talar body (apex of the fornix) with concomitant bone defects and cystic changes are found on X-ray, computed tomography (CT), or magnetic resonance imaging, it is important to accurately determine the nature of the lesion and make a correct diagnosis for the treatment and prognosis of the patient. The purpose of this study was to explore the imaging features of three-phase single-photon emission computed tomography (SPECT)/CT images of cystic lesions of the talus.

methodsA total of 189 patients with chronic pain in the ankle joint suspected to be caused by cystic degeneration of the talus were enrolled. All patients underwent 99mTc-methyl diphosphonate (99mTc-MDP) three-phase SPECT/CT bone imaging and delayed scans in our hospital. The location, range of involvement, classification, CT value, and radioactivity uptake of the sclerotic areas of cystic lesions on the talus, and the continuity of the articular surface, were recorded. All recorded parameters were analyzed in comparison with pathological results.

resultsEighty-three percent (157/189) of the talar cysts were located on the medial fornix, largely involving the anterior middle part (43.27%), with larger cysts involving the posterior part (9.6%). Sixty-three percent (119/189) of the patients had type I lesions and 37% (70/189) had type II lesions. The articular surface of the medial dome of the talus was intact in all patients, but the subchondral bony articular surface was rough in 88% (166/189) of patients. The coincidence rate for the location, type, and range of involvement of cystic lesions with the pathological results was 87.83% (166/189). The mean CT value of the cystic lesions was 45 ± 15 HU (30-60 HU). The percentages of pathological chondrogenesis in high CT value ≥ 50 HU (19/70) and low CT value < 50 HU (51/70) groups were 89.47% (17/19) and 29.14% (15/51) (χ

conclusionsThree-phase bone imaging could identify damage of the talus caused by cystic degeneration, while delayed SPECT/CT images showed advantages for displaying bone microstructure, blood supplement, and bone metabolism when examining the location, range of involvement, classification, and repair of cystic lesions of the talus.

Indexed as

CystsTalusHumansMagnetic Resonance ImagingTechnetium Tc 99m MedronateTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedTechnetium Tc 99m MedronateCystic degenerationDiagnosisSPECT/CTTalusTreatment

Identifiers

PMID36224613
PMCPMC9554967
OpenAlexW4304690614

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.