Evidence map›Paper›PMID 36224336›Full record

ArticleSpinal cord2023

Sex differences in urological management during spinal cord injury rehabilitation: results from a prospective multicenter longitudinal cohort study.

Collene E Anderson, Veronika Birkhäuser, Martina D Liechti, Xavier Jordan, Eugenia Luca, Sandra Möhr, Jürgen Pannek, Thomas M Kessler, Martin W G Brinkhof

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Spinal cord, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Collene E AndersonSwiss Paraplegic Research, Nottwil, Switzerland.ORCID 0000-0002-4350-6816
Veronika BirkhäuserDepartment of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.ORCID 0000-0002-6646-7266
Martina D LiechtiDepartment of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.ORCID 0000-0002-3024-0975
Xavier JordanClinique Romande de Réadaptation, Sion, Switzerland.
Eugenia LucaClinique Romande de Réadaptation, Sion, Switzerland.
Sandra MöhrNeuro-Urology, REHAB Basel, Basel, Switzerland.
Jürgen PannekDepartment of Neuro-Urology, Swiss Paraplegic Center, Nottwil, Switzerland.ORCID 0000-0002-9910-1295
Thomas M Kessler *Department of Neuro-Urology, Balgrist University Hospital, University of Zürich, Zürich, Switzerland.ORCID 0000-0002-1991-5919
Martin W G Brinkhof *Swiss Paraplegic Research, Nottwil, Switzerland. martin.brinkhof@paraplegie.ch.ORCID 0000-0002-9319-665X
University of Zurich · CHClinique Romande de Réadaptation · CHUniversity of Lucerne · CHSwiss Paraplegic Center · CHUniversity of Bern · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 33IC30_179644Swiss National Science Foundation 179644
6 · The paper itself

Abstract

STUDY

designProspective, multicenter, longitudinal cohort study.

objectivesTo describe female-male differences in first-line urological management during spinal cord injury (SCI) rehabilitation.

settingInpatient specialized post-acute SCI rehabilitation in Switzerland.

methodsData on bladder storage medication (antimuscarinic and beta-3 agonist) use, suprapubic catheter placement, demographic and SCI characteristics was collected within 40 days of SCI and at rehabilitation discharge from May 2013-September 2021. Prevalence and indicators of bladder storage medication and suprapubic catheter use at discharge were investigated with sex-stratified descriptive and logistic regression analyses.

resultsIn 748 patients (219 females, 29%), bladder storage medication use at discharge had a prevalence of 24% (95% CI: 18-29%) for females and 30% (95% CI: 26-34%) for males and was indicated by cervical AIS grade A, B, C and traumatic SCI in both sexes. Thoracic AIS grade A, B, C SCI (males), and lumbar/sacral AIS grade A, B, C SCI (females) predicted higher odds of bladder storage medication use (SCI characteristic*sex interaction, p < 0.01). Prevalence of suprapubic catheter use at discharge was 22% (95% CI: 17-28%) for females and 17% (95% CI: 14-20%) for males. Suprapubic catheter use was indicated by cervical AIS grade A, B, C SCI, and age >60 in both sexes. Females with thoracic grade A, B, C SCI tended to have higher odds of suprapubic catheter use (SCI characteristic*sex interaction, p = 0.013).

conclusionsWe identified sex differences in urological management especially in persons with AIS grade C or higher sub-cervical SCI. There is scope for well-powered, female-specific research in SCI in order to understand the underlying mechanisms and support patient-tailored management.

Indexed as

Spinal Cord InjuriesCohort StudiesFemaleHumansLongitudinal StudiesMaleProspective StudiesSex Characteristics

Identifiers

PMID36224336
PMCPMC7614058
OpenAlexW4304694417

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.