ArticleScientific reports2022
Zn (II)-porphyrin-based photochemically green synthesis of novel ZnTPP/Cu nanocomposites with antibacterial activities and cytotoxic features against breast cancer cells.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Modulation of Self-Assembly and Enhanced Photocatalytic HChemSusChem · 2025Article
- Microbial infection and treatment strategies in cancer patients.Frontiers in microbiology · 2025Review
- Biomaterials-based phototherapy for bacterial infections.Frontiers in pharmacology · 2024Review
- Facile photosynthesis of novel porphyrin-derived nanocomposites containing Ag, Ag/Au, and Ag/Cu for photobactericidal study.Scientific reports · 2023Article
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4 authors.
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Abstract
This study focuses on synthesizing novel nanocomposites, zinc(II)tetrakis(4-phenyl)porphyrin/Cu nanoparticles (ZnTPP/Cu-NPs),with antibacterial activity, fabricated through a single-step green procedure. In this regard, the self-assembly of ZnTPP was carried out through an acid-base neutralization method to prepare ZnTPP nanoparticles. Then, the copper nanoparticles (Cu-NPs) were grown on ZnTPP nanoparticles through a visible-light irradiated photochemical procedure in the absence and presence of polyacrylic acid (PAA) as a modulator. The effect of PAA on the morphological properties of the prepared nanocomposites was evaluated. Eventually, the antibacterial activity of nanocomposites with different morphologies was investigated. In this way, the average zone of inhibition growth of diameter, minimum inhibitory concentration, and minimum bactericidal concentration values was determined. Besides, the cytotoxicity of the nanocomposites was evaluated by (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay MCF-7and (HEK-293) cell lines. The specific features of the synthesized nanocomposites identified them as antibacterial compounds which have therapeutic effects on breast cancer.
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