ArticleCommunications biology2022
A ventral stream-prefrontal cortex processing cascade enables working memory gating dynamics.
Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Pharmacological modulation of directed network communication and neural hubs in action-effect integration.The international journal of neuropsychopharmacology · 2025Trial
- Auricular Transcutaneous Vagus Nerve Stimulation Specifically Enhances Working Memory Gate Closing Mechanism: A System Neurophysiological Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Trial
- Memory in Psychiatric Disorders: A Review.Life (Basel, Switzerland) · 2025Review
- Working Memory Updating in the Macaque Lateral Prefrontal Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Dynamic Management of Working Memory Is Supported by Aperiodic Neural Activity.Psychophysiology · 2025Article
- Variations in neuronal cytoskeletal integrity affect directed communication in distributed networks during inhibitory control.Communications biology · 2025Article
- The metacontrol of event segmentation-A neurophysiological and behavioral perspective.Human brain mapping · 2024Article
- Neurophysiological effective network connectivity supports a threshold-dependent management of dynamic working memory gating.iScience · 2024Article
- Response stopping under conflict: The integrative role of representational dynamics associated with the insular cortex.Human brain mapping · 2024Article
- The relationship between changes in functional connectivity gradients and cognitive-emotional disorders in sudden sensorineural hearing loss.Brain communications · 2024Article
- Resting network architecture of theta oscillations reflects hyper-learning of sensorimotor information in Gilles de la Tourette syndrome.Brain communications · 2024Article
- Cognitive neuroscience perspective on memory: overview and summary.Frontiers in human neuroscience · 2023Article
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Authors and funding
4 authors.
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Abstract
The representation of incoming information, goals and the flexible processing of these are required for cognitive control. Efficient mechanisms are needed to decide when it is important that novel information enters working memory (WM) and when these WM 'gates' have to be closed. Compared to neural foundations of maintaining information in WM, considerably less is known about what neural mechanisms underlie the representational dynamics during WM gating. Using different EEG analysis methods, we trace the path of mental representations along the human cortex during WM gate opening and closing. We show temporally nested representational dynamics during WM gate opening and closing depending on multiple independent neural activity profiles. These activity profiles are attributable to a ventral stream-prefrontal cortex processing cascade. The representational dynamics start in the ventral stream during WM gate opening and WM gate closing before prefrontal cortical regions are modulated. A regional specific activity profile is shown within the prefrontal cortex depending on whether WM gates are opened or closed, matching overarching concepts of prefrontal cortex functions. The study closes an essential conceptual gap detailing the neural dynamics underlying how mental representations drive the WM gate to open or close to enable WM functions such as updating and maintenance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.