Evidence map›Paper›PMID 36224173›Full record

ArticleNature communications2022

Outcomes among confirmed cases and a matched comparison group in the Long-COVID in Scotland study.

Claire E Hastie, David J Lowe, Andrew McAuley, Andrew J Winter, Nicholas L Mills, Corri Black, Janet T Scott, Catherine A O'Donnell, David N Blane, Susan Browne and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 128 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 8 pooled it
26.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 8 syntheses or guidelines pooled it, 212 citations in OpenAlex.

  1. Pooled it
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  5. Pathophysiological Mechanisms in Long COVID: A Mixed Method Systematic Review.International journal of environmental research and public health · 2024
    Pooled it
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  8. Long-Term Consequences of Asymptomatic SARS-CoV-2 Infection: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
    Pooled it
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68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Claire E HastieInstitute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
David J LoweInstitute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
Andrew McAuleyPublic Health Scotland, Meridian Court, Glasgow, G2 6QQ, UK.
Andrew J WinterSandyford Sexual Health Services, NHS Greater Glasgow and Clyde, Glasgow, G3 7NB, UK.ORCID 0000-0002-8293-9462
Nicholas L MillsBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SU, UK.ORCID 0000-0003-0533-7991
Corri BlackAberdeen Centre for Health Data Science, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
Janet T ScottMRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, G61 1QH, UK.
Catherine A O'DonnellInstitute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
David N BlaneInstitute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.ORCID 0000-0002-3872-3621
Susan BrowneInstitute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
Tracy R IbbotsonInstitute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
Jill P PellInstitute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK. Jill.pell@glasgow.ac.uk.ORCID 0000-0002-8898-7035
University of Glasgow · GBGlasgow Caledonian University · GBMRC University of Glasgow Centre for Virus Research · GBNHS Greater Glasgow and Clyde · GBQueen Elizabeth University Hospital · GBUniversity of Aberdeen · GBUniversity of Edinburgh · GB

Funding

British Heart Foundation CH/F/21/90010British Heart Foundation RE/18/5/34216British Heart Foundation RG/20/10/34966Chief Scientist Office COV/LTE/20/06
6 · The paper itself

Abstract

With increasing numbers infected by SARS-CoV-2, understanding long-COVID is essential to inform health and social care support. A Scottish population cohort of 33,281 laboratory-confirmed SARS-CoV-2 infections and 62,957 never-infected individuals were followed-up via 6, 12 and 18-month questionnaires and linkage to hospitalization and death records. Of the 31,486 symptomatic infections,1,856 (6%) had not recovered and 13,350 (42%) only partially. No recovery was associated with hospitalized infection, age, female sex, deprivation, respiratory disease, depression and multimorbidity. Previous symptomatic infection was associated with poorer quality of life, impairment across all daily activities and 24 persistent symptoms including breathlessness (OR 3.43, 95% CI 3.29-3.58), palpitations (OR 2.51, OR 2.36-2.66), chest pain (OR 2.09, 95% CI 1.96-2.23), and confusion (OR 2.92, 95% CI 2.78-3.07). Asymptomatic infection was not associated with adverse outcomes. Vaccination was associated with reduced risk of seven symptoms. Here we describe the nature of long-COVID and the factors associated with it.

Indexed as

COVID-19FemaleHospitalizationHumansPost-Acute COVID-19 SyndromeQuality of LifeSARS-CoV-2

Identifiers

PMID36224173
PMCPMC9556711
OpenAlexW4304689170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.