Evidence map›Paper›PMID 36223973›Full record

ArticleBMJ case reports2022

Metastatic triple negative breast cancer with NTRK gene fusion on tissue but not on ctDNA molecular profile.

Nupur Singh, Rishika Singh, Brennan Decker, David Robins, Gregory Vidal

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nupur SinghCollege of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA nsingh8@uthsc.edu.
Rishika SinghCollege of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Brennan DeckerWest Cancer Center and Research Institute, Memphis, TN, USA.
David RobinsWest Cancer Center and Research Institute, Memphis, TN, USA.
Gregory VidalCollege of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
West Cancer Center · USUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A woman presented to medical oncology with almost 4 years of untreated, slowly progressing, triple negative metastatic breast cancer to the lung. About 15 years prior, she was diagnosed with invasive ductal carcinoma of the right breast with ipsilateral chest wall recurrence 6 years later. Comprehensive molecular profiling of a metastatic lesion detected a hotspot

Indexed as

Breast NeoplasmsCirculating Tumor DNATriple Negative Breast NeoplasmsCarcinomaFemaleGene FusionHumansOncogene Proteins, FusionProtein Kinase InhibitorsCirculating Tumor DNAOncogene Proteins, FusionProtein Kinase InhibitorsBreast cancerDrugs and medicinesScreening (oncology)

Identifiers

PMID36223973
PMCPMC9562290
OpenAlexW4304695555

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.