Evidence map›Paper›PMID 36223967›Full record

SynthesisBMJ open2022

Burden of atrial fibrillation among adults with heart failure in sub-Saharan Africa: a systematic review and meta-analysis.

Valirie Ndip Agbor, Frank-Leonel Tianyi, Leopold Ndemnge Aminde, Clarence Mvalo Mbanga, Saint Just N Petnga, Larissa Pone Simo, Anastase Dzudie, Muchi Ditah Chobufo, Jean Jacques Noubiap

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 4 countries.

Valirie Ndip AgborNuffield Department of Population Health, University of Oxford, Oxford, UK nvagbor@gmail.com.ORCID 0000-0002-6708-6852
Frank-Leonel TianyiNuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID 0000-0001-5687-5285
Leopold Ndemnge AmindeSchool of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia.ORCID 0000-0003-2787-7518
Clarence Mvalo MbangaMankon Sub-divisional Hospital, Bamenda, North West Region, Cameroon.
Saint Just N PetngaKousseri Regional Hospital, Far-North Regional Delegation for Health, Kousseri, Cameroon.
Larissa Pone SimoGeneral Practice, Dzeng Sub-divisional Hospital, Dzeng, Centre Region, Cameroon.
Anastase DzudieCardiology and Cardiac Pacing Unit, Department of Medicine, Douala General Hospital, Douala, Cameroon.ORCID 0000-0003-4038-4128
Muchi Ditah ChobufoDepartment of Cardiovascular Diseases Heart and Vascular Institute, West Virginia University, Morgantown, West Virginia, USA.
Jean Jacques NoubiapCentre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute (SAHMRI), University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia, University of Adelaide CHRD, Adelaide, South Australia, Australia.ORCID 0000-0002-7722-9757
Griffith University · AURoyal Adelaide Hospital · AUUniversity of Bamenda · CMUniversity of Buea · CMUniversity of Douala · CMUniversity of Oxford · GBWest Virginia University · USYaoundé General Hospital · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to estimate the prevalence of atrial fibrillation (AF) in adults with heart failure (HF) and summarise the all-cause mortality ratio among adult patients with coexisting HF and AF in sub-Saharan Africa (SSA).

settingThis was a systematic review and meta-analysis of cross-sectional and cohort studies with primary data on the prevalence and incidence of AF among patients with HF and the all-cause mortality ratio among patients with HF and AF in SSA. We combined text words and MeSH terms to search MEDLINE, PubMed and Global Health Library through Ovid SP, African Journals Online and African Index Medicus from database inception to 10 November 2021. Random-effects meta-analysis was used to estimate pooled prevalence. PRIMARY OUTCOME MEASURES: The prevalence and incidence of AF among patients with HF, and the all-cause mortality ratio among patients with HF and AF.

resultsTwenty-seven of the 1902 records retrieved from database searches were included in the review, totalling 9987 patients with HF. The pooled prevalence of AF among patients with HF was 15.6% (95% CI 12.0% to 19.6%). At six months, the all-cause mortality was 18.4% (95% CI 13.1% to 23.6%) in a multinational registry and 67.7% (95% CI 51.1% to 74.3%) in one study in Tanzania. The one-year mortality was 48.6% (95% CI 32.5% to 64.7%) in a study in the Democratic Republic of Congo. We did not find any study reporting the incidence of AF in HF.

conclusionAF is common among patients with HF in SSA, and patients with AF and HF have poor survival. There is an urgent need for large-scale population-based prospective data to reliably estimate the prevalence, incidence and risk of mortality of AF among HF patients in SSA to better understand the burden of AF in patients with HF in the region. PROSPERO REGISTRATION NUMBER: CRD42018087564.

Indexed as

Atrial FibrillationHeart FailureAdultCross-Sectional StudiesHumansProspective StudiesTanzaniaadult cardiologyepidemiologyheart failure

Identifiers

PMID36223967
PMCPMC9562316
OpenAlexW4304808574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.