Evidence map›Paper›PMID 36223603›Full record

ArticleOcular immunology and inflammation2024

Isolated Optic Disc Granuloma as a Presenting Sign of Sarcoidosis.

Enny Oyeniran, David Katz, Shilpa Kodati

Open access · greenAbstract readCase Reports
In one paragraph

Article in Ocular immunology and inflammation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Sarcoidosis-Related Uveitis: A Review.Journal of clinical medicine · 2023
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Enny OyeniranNational Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
David KatzNeurology and Neuro-Ophthalmology, Bethesda Neurology, Rockville, Maryland, USA.
Shilpa KodatiNational Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
National Institutes of Health · USMaryland Oncology Hematology · US

Funding

Studies of Ocular inflammation: Translational ResearchZIAEY000556 · NEI · NATIONAL EYE INSTITUTE · PI CASPI, RACHEL R. · 2017 to 2025
$11.3M
Intramural NIH HHS ZIA EY000556
6 · The paper itself

Abstract

purposeTo report a case of an optic disc granuloma secondary to sarcoidosis in the absence of any systemic symptoms nor evident signs of intraocular inflammation at the time of presentation.

methodsRetrospective case report.

resultsA 59-year-old Caucasian woman with previously unrevealing systemic work up was referred to the uveitis service for persistent optic disc edema of the right eye for over 1 year. Fundoscopic examination revealed an optic disc granuloma with associated hyper-reflectivity on OCT and high surface reflectivity with medium internal reflectivity on B-scan ultrasound. CT chest was negative, however, a PET scan demonstrated extensive FDG activity in the mediastinum and bilateral hilum, consistent with a diagnosis of sarcoidosis.

conclusionOptic nerve head granulomas can rarely present as the only clinical sign of sarcoidosis. In these cases, additional imaging modalities may be needed to make the appropriate diagnosis.

Indexed as

Optic DiskSarcoidosisUveitisFemaleGranulomaHumansMiddle AgedRetrospective StudiesNeuro-sarcoidosisoptic disc granulomaoptic nerve granulomasarcoidosissarcoid uveitis

Identifiers

PMID36223603
PMCPMC10090223
OpenAlexW4304756906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.