Evidence map›Paper›PMID 36223485›Full record

ArticleJournal of fish diseases2022

Immersion challenge model for Flavobacterium psychrophilum infection of Atlantic salmon (Salmo salar L.) fry.

Valeria Macchia, Makoto Inami, Anne Ramstad, Fabian Grammes, Andrew Reeve, Thomas Moen, Jacob Seilø Torgersen, Alexandra Adams, Andrew P Desbois, Rowena Hoare

Open access · hybridAbstract read
In one paragraph

Article in Journal of fish diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  5. VaryingMicrobiology spectrum · 2024
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  6. Secreted Extracellular Products ofPathogens (Basel, Switzerland) · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Valeria MacchiaInstitute of Aquaculture, University of Stirling, Stirling, UK.ORCID https://orcid.org/0000-0002-3693-322X
Makoto InamiVESO Vikan, Namsos, Norway.
Anne RamstadVESO Vikan, Namsos, Norway.
Fabian GrammesAquaGen, Trondheim, Norway.ORCID https://orcid.org/0000-0002-9551-9280
Andrew ReeveAquaGen Scotland Ltd, Stirling University Innovation Park, Stirling, UK.
Thomas MoenAquaGen, Trondheim, Norway.
Jacob Seilø TorgersenAquaGen, Trondheim, Norway.ORCID https://orcid.org/0000-0002-6758-2979
Alexandra AdamsInstitute of Aquaculture, University of Stirling, Stirling, UK.ORCID https://orcid.org/0000-0002-2469-3310
Andrew P DesboisInstitute of Aquaculture, University of Stirling, Stirling, UK.ORCID https://orcid.org/0000-0001-6052-8761
Rowena HoareInstitute of Aquaculture, University of Stirling, Stirling, UK.ORCID https://orcid.org/0000-0002-9298-4275
University of Stirling · GBAquaGen (Norway) · NONorwegian Veterinary Centre for Contract Research and Commercial Services · NO

Funding

AquaGen Scotland LtdSustainable Aquaculture Innovation Centre (SAIC)University of Stirling
6 · The paper itself

Abstract

Flavobacterium psychrophilum is the causative agent of bacterial cold-water disease (CWBD) and rainbow trout fry syndrome (RTFS), which affect salmonids. To better understand this pathogen and its interaction with the host during infection, including to support the development of resistant breeds and new vaccines and treatments, there is a pressing need for reliable and reproducible immersion challenge models that more closely mimic natural routes of infection. The aim of this present study was to evaluate a challenge model developed previously for rainbow trout for use in Atlantic salmon. First, preliminary challenges were conducted in Atlantic salmon (n = 120) and rainbow trout (n = 80) fry using two F. psychrophilum isolates collected from each fish species, respectively; fish had been pretreated with 200 mg/L hydrogen peroxide for 1 h. Thereafter, the main challenge was performed for just one F. psychrophilum isolate for each species (at 2 × 10

Indexed as

Fish DiseasesFlavobacteriaceae InfectionsOncorhynchus mykissSalmo salarAnimalsFlavobacteriumHydrogen PeroxideImmersionReproducibility of ResultsWaterHydrogen PeroxideWaterAtlantic salmonbacterial cold-water disease (BCWD)Flavobacterium psychrophilumrainbow trout fry syndrome (RTFS)

Identifiers

PMID36223485
PMCPMC9804593
OpenAlexW4292080293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.