Evidence map›Paper›PMID 36223447›Full record

ReviewScience translational medicine2022

Translating diagnostics and drug delivery technologies to low-resource settings.

Erin M Euliano, Alexandros A Sklavounos, Aaron R Wheeler, Kevin J McHugh

Abstract readReview
In one paragraph

Review in Science translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Ultrasensitive Enzyme-Free Detection of Proteins on Magnetic Beads.Journal of the American Chemical Society · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Biochemically Programmable Isothermal PCR.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erin M EulianoDepartment of Bioengineering, Rice University, Houston, TX 77005, USA.ORCID 0000-0002-9423-8591
Alexandros A SklavounosDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0000-0003-1495-7156
Aaron R WheelerDepartment of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.ORCID 0000-0001-5230-7475
Kevin J McHughDepartment of Bioengineering, Rice University, Houston, TX 77005, USA.ORCID 0000-0001-6801-4431

Funding

Biomaterial Strategies for Modulating the Immune ResponseK22AI146215 · NIAID · RICE UNIVERSITY · PI MCHUGH, KEVIN JAMES · 2020 to 2021
$267k
Research Supplement to Promote Diversity: Carlos Torres (R03EB031495 Parent Award)R03EB031495 · NIBIB · RICE UNIVERSITY · PI MCHUGH, KEVIN JAMES · 2021 to 2022
$176k
NIAID NIH HHS K22 AI146215NIBIB NIH HHS R03 EB031495
6 · The paper itself

Abstract

Diagnostics and drug delivery technologies engineered for low-resource settings aim to meet their technical design specifications using strategies that are compatible with limited equipment, infrastructure, and operator training. Despite many preclinical successes, very few of these devices have been translated to the clinic. Here, we identify factors that contribute to the clinical success of diagnostics and drug delivery systems for low-resource settings, including the need to engage key stakeholders at an early stage, and provide recommendations for the clinical translation of future medical technologies.

Indexed as

Drug Delivery Systems

Identifiers

PMID36223447
PMCPMC9716722

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.