ArticlePloS one2022
Physical activity mitigates the link between adverse childhood experiences and depression among U.S. adults.
Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Adverse childhood experiences and adolescent physical activity: mechanisms and intervention opportunities.World journal of pediatrics : WJP · 2026Article
- Associations between adverse childhood experiences and physical activity domains among middle-aged and older adults: a national analysis.BMC public health · 2026Article
- Childhood trauma exposure, working memory updating, and exercise experience in adolescents with major depressive disorder.BMC psychology · 2025Article
- Associations of adverse childhood experiences with midlife cardiovascular health in women.American journal of preventive cardiology · 2025Article
- Combined lifestyle, childhood trauma and depressive symptoms in adults with subthreshold depression: a prospective cohort study.Epidemiology and psychiatric sciences · 2025Article
- Lifestyle health behaviors and experience of depression among middle and high school students in South Korea: A comparison between 2010-2013 and 2020-2023.Preventive medicine reports · 2025Article
- Toward a Trauma-Informed Comprehensive School Physical Activity Program: Specifying Feasible Practices Across the School Day.The Journal of school health · 2025Article
- Association between Depressive Symptoms, Physical Activity, and Health Factors in Hispanic Emerging Adults.International journal of environmental research and public health · 2024Article
- Variety ACEs and risk of developing anxiety, depression, or anxiety-depression co-morbidity: the 2006-2022 UK Biobank data.Frontiers in psychiatry · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdverse Childhood Experiences (ACEs) include potentially traumatic exposures to neglect, abuse, and household problems involving substance abuse, mental illness, divorce, incarceration, and death. Past study findings suggest ACEs contribute to depression, while physical activity alleviates depression. Little is known about the link between ACEs and physical activity as it relates to depression among U.S. adults. This research had a primary objective of determining the role of physical activity within the link between ACEs and depression. The significance of this study involves examining physical activity as a form of behavioral medicine.
methodsData from the 2020 Behavioral Risk Factor Surveillance System were fit to Pearson chi-square and multivariable logistic regression models to examine the links between ACEs and depression, ACEs and physical activity, and physical activity and depression among U.S. adults ages 18-and-older (n = 117,204) from 21 states and the District of Columbia, while also determining whether physical activity attenuates the association between ACEs and depression.
resultsFindings from chi-square analyses indicated that ACEs are related to physical activity (χ2 = 19.4, df = 1; p<0.01) and depression (χ2 = 6,841.6, df = 1; p<0.0001). Regression findings suggest ACEs were linked to depression (AOR = 1.050; 95% CI = 1.049, 1.051). ACEs and physical activity (AOR = 0.994; 95% CI = 0.992, 0.995) and physical activity and depression (AOR = 0.927; 95% CI = 0.922, 0.932) were both inversely related. Physical activity mitigated the link between ACEs and depression (AOR = 0.995; 95% CI = 0.993, 0.996).
conclusionsThis research addressed a critical knowledge gap concerning how ACEs and physical activity contribute to depression outcomes among U.S. adults. Findings suggest physical activity mitigates the effect of ACEs on depression. Future studies should apply physical activity interventions to alleviate depression among U.S. adults with high ACEs.
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