Evidence map›Paper›PMID 36223284›Full record

ArticleAnnals of medicine2022

Pulse pressure and all-cause mortality in ischaemic heart failure patients: a prospective cohort study.

Weida Qiu, Xiaoju Xiao, Anping Cai, Zhiping Gao, Liwen Li

Open access · goldAbstract read
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Article in Annals of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Weida QiuThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Xiaoju XiaoThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Anping CaiDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.ORCID 0000-0002-5587-5811
Zhiping GaoConcord Medical Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Liwen LiDepartment of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Guangdong Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether the association between pulse pressure (PP) and mortality varies with systolic blood pressure (SBP) in ischaemic heart failure (HF) with left ventricular systolic dysfunction (LVSD) is unknown.

objectiveTo evaluate the association between PP and all-cause mortality in ischaemic HF patients with SBP status at admission. PATIENTS AND

methodsThis prospective cohort study included 1581 ischaemic HF patients with LVSD. A total of 23.3% (

resultsAfter a median of follow-up of 3.0 years, 257 events (16.4%) were observed in the cohort. There was a J-shaped relationship between PP and all-cause mortality (P value for nonlinearity = 0.020), with a risk nadir of approximately 46-49 mmHg. All-cause mortality risk varied with SBP status. Higher PP was associated with worse prognosis when the SBP was ≥110 mmHg, whereas the relationship did not reach statistical significance when the SBP was <110 mmHg.

conclusionA J-shaped relationship between PP and all-cause mortality was observed in ischaemic HF patients with LVSD, and higher PP was associated with worse prognosis only in those with SBP ≥110 mmHg. Further studies are needed to corroborate these findings.KEY MESSAGESA J-shaped relationship between pulse pressure and all-cause mortality was observed in ischaemic heart failure patients with left ventricular systolic dysfunction, with a risk nadir of approximately 46-49 mmHg.All-cause mortality risk varied with systolic blood pressure status, and higher pulse pressure was associated with worse prognosis when systolic blood pressure was above 110 mmHg.

Indexed as

Heart FailureHypertensionVentricular Dysfunction, LeftBlood PressureCohort StudiesFemaleHumansMalePrognosisProportional Hazards ModelsProspective Studiesblood pressureischaemic heart failureleft ventricular systolic dysfunctionPulse pressure

Identifiers

PMID36223284
PMCPMC9559321
OpenAlexW4304758178

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.