Evidence map›Paper›PMID 36223199›Full record

ArticleBiochemistry2022

Metabolites of Cannabigerol Generated by Human Cytochrome P450s Are Bioactive.

Pritam Roy, David G Dennis, Mark D Eschbach, Shravanthi D Anand, Fengyun Xu, Jonathan Maturano, Judith Hellman, David Sarlah, Aditi Das

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Minor cannabinoids CBD, CBG, CBN, and CBC differentially modulate sensory neuron activation.The Journal of pharmacology and experimental therapeutics · 2026
    Article
  3. Pharmacokinetic and pharmacodynamic properties of cannabigerol in male mice.The Journal of pharmacology and experimental therapeutics · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Pritam RoyDepartment of Comparative Biosciences, Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, Department of Bioengineering, Neuroscience program, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.
David G DennisRoger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States.
Mark D EschbachDepartment of Comparative Biosciences, Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, Department of Bioengineering, Neuroscience program, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.
Shravanthi D AnandDepartment of Comparative Biosciences, Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, Department of Bioengineering, Neuroscience program, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.
Fengyun XuDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94143, United States.
Jonathan MaturanoRoger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States.
Judith HellmanDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California 94143, United States.
David SarlahRoger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States.ORCID 0000-0002-8736-8953
Aditi DasDepartment of Comparative Biosciences, Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, Department of Bioengineering, Neuroscience program, University of Illinois Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0002-6731-6726
Georgia Institute of Technology · USUniversity of Illinois Urbana-Champaign · USUniversity of California, San Francisco · US

Funding

The study of Gpr149 in nociception and the peripheral action of minor cannabinoidsR01AT010757 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HELLMAN, JUDITH, SCHUMACHER, MARK A · 2019 to 2023
$3.0M
Biochemical Mechanism of Eicosanoid Synthesizing EnzymesR01GM115584 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI DAS, ADITI · 2017 to 2022
$1.7M
Systematic Investigation of Rare Cannabinoids with Pain ReceptorsR21AT010761 · NCCIH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI DAS, ADITI, SARLAH, DAVID · 2019 to 2020
$404k
NCCIH NIH HHS R01 AT010757NCCIH NIH HHS R21 AT010761NIGMS NIH HHS R01 GM115584
6 · The paper itself

Abstract

The phytocannabinoid cannabigerol (CBG) is the central biosynthetic precursor to many cannabinoids, including Δ

Indexed as

CannabidiolCannabinoidsAnimalsCytochrome P-450 Enzyme SystemHumansMiceCannabidiolcannabigerolCannabinoidsCytochrome P-450 Enzyme System

Identifiers

PMID36223199
PMCPMC10337483
OpenAlexW4304698208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.